Variables | Cases/person-years | Regression coefficient | HR (95% CI) | P-value | Points assigned |
---|---|---|---|---|---|
Age at baseline, years | |||||
 40–44 | 168/845,021 |  | Reference |  | 0.0 |
 45–49 | 236/687,811 | 0.47 | 1.59 (1.31 to 1.94) | < 0.001 | 4.6 |
 50–54 | 473/860,063 | 0.87 | 2.39 (2.00 to 2.86) | < 0.001 | 8.6 |
 55–59 | 593/666,252 | 1.33 | 3.79 (3.18 to 4.52) | < 0.001 | 13.2 |
 60–64 | 572/454,473 | 1.67 | 5.29 (4.43 to 6.30) | < 0.001 | 16.5 |
 65–69 | 570/357,890 | 1.90 | 6.71 (5.62 to 8.01) | < 0.001 | 18.8 |
 70–75 | 477/236,230 | 2.13 | 8.42 (7.02 to 10.11) | < 0.001 | 21.1 |
Sex | |||||
 Women | 1033/2,447,930 |  | Reference |  | 0.0 |
 Men | 2056/1,659,810 | 0.87 | 2.39 (2.15 to 2.66) | < 0.001 | 8.6 |
Education | |||||
 College or above | 102/209,414 |  | Reference |  | 0.0 |
 High school | 310/630,316 | 0.40 | 1.49 (1.19 to 1.87) | < 0.001 | 4.0 |
 Middle school | 664/1,088,309 | 0.54 | 1.72 (1.39 to 2.12) | < 0.001 | 5.3 |
 Illiterate or primary school | 2013/2,179,701 | 0.67 | 1.95 (1.58 to 2.39) | < 0.001 | 6.6 |
BMI | |||||
 ≥ 18.5 | 2885/3,943,563 |  | Reference |  | 0.0 |
 < 18.5 | 204/164,177 | 0.25 | 1.28 (1.11 to 1.48) | < 0.001 | 2.5 |
Pack-years of smoking | |||||
 Never (0 pack-year) | 1389/2,772,929 |  | Reference |  | 0.0 |
 > 0 to < 20 pack-years | 559/536,569 | 0.12 | 1.13 (1.00 to 1.27) | 0.049 | 1.2 |
 ≥ 20 pack-years | 1141/798,243 | 0.22 | 1.25 (1.12 to 1.39) | < 0.001 | 2.2 |
Alcohol drinking per daya | |||||
 Never or light | 2598/3,750,542 |  | Reference |  | 0.0 |
 Moderate or heavy | 491/357,198 | 0.17 | 1.19 (1.07 to 1.32) | 0.001 | 1.7 |
Intake of fresh vegetables and fruitsb | |||||
 Frequent | 695/1,134,030 |  | Reference |  | 0.0 |
 Occasional | 2394/2,973,710 | 0.10 | 1.11 (1.01 to 1.21) | 0.027 | 1.0 |
Intake of salty foodsc | |||||
 Occasional | 2105/3,146,493 |  | Reference |  | 0.0 |
 Frequent | 984/961,247 | 0.40 | 1.50 (1.39 to 1.62) | < 0.001 | 4.0 |
Previous cancer diagnosis | |||||
 No | 3042/4,089,431 |  | Reference |  | 0.0 |
 Yes | 47/18,309 | 1.09 | 2.96 (2.22 to 3.95) | < 0.001 | 10.7 |
Family history of cancer in first-degree relatives | |||||
 No | 2328/3,366,039 |  | Reference |  | 0.0 |
 Yes | 761/741,701 | 0.40 | 1.50 (1.38 to 1.63) | < 0.001 | 4.0 |
History of peptic ulcer | |||||
 No | 2844/3,939,709 |  | Reference |  | 0.0 |
 Yes | 245/168,031 | 0.47 | 1.59 (1.40 to 1.82) | < 0.001 | 4.6 |