Skip to main content
Fig. 6 | BMC Medicine

Fig. 6

From: Single-cell sequencing reveals the immune microenvironment landscape related to anti-PD-1 resistance in metastatic colorectal cancer with high microsatellite instability

Fig. 6

IL-1β antagonist and PD-1 inhibitor have a synergistic antitumor effect. A Diagram of the experimental timeline. B Xenograft tumors of BALB/c mice 16 days after inoculation with CT26 cells containing an empty vector or IL-1β overexpression vector (n = 5). C Tumor weight (n = 5). D Average body weight and average tumor volume of BALB/c mice in each treatment group (n = 5). E Hematoxylin–eosin staining of tumors from inoculated BALB/c mice (n = 5). *P < 0.05; **P < 0.01; ***P < 0.001; ****P < 0.0001

Back to article page