Fig. 7From: Single-cell sequencing reveals the immune microenvironment landscape related to anti-PD-1 resistance in metastatic colorectal cancer with high microsatellite instabilityIL-1β stimulates the aggregation of MDSCs and inhibits the proliferation of CD8+ T cells in tumors. A Flow cytometry was performed to detect PMN-MDSCs, M-MDSCs, and CD8 + T cells (n = 5). Quantitative statistical diagram for expression of (B) PMN-MDSCs, (C) M-MDSCs, (D) CD8.+ T cells in each group (n = 5). *P < 0.05; **P < 0.01; ***P < 0.001; ****P < 0.0001Back to article page