Table 1 Included genome-wide association data sources

Height

Measured or self-reported

Per SD (cm)

76% EUR, 9% EAS, 8% HIS, 5% AFR, 1% SAS

5,380,080

[17, 18]

ANP

Relative aptamer abundance in plasma

Per SD (RFU)

100% EUR

35,559

[19, 20]

BNP

[19, 21]

NT-pro-BNP

Plasma Olink proximity extension assay

Per SD (NPX)

100% EUR

21,758

[22, 23]

CAD

ACS, CAD, or MI. Medical records^a or self-report

Case status^b

 ~ 85% EUR, 15% EAS

1,378,170 (210,842)

[24, 25]

Stroke

All-cause. Medical records or self-report

Case status^b

67% EUR, 25% EAS, 4% AFR, 3% SAS, 1% HIS

1,614,080 (110,182)

[25, 26]

HF

Medical records. Study-based adjudicated self-report

Case status^b

 > 99% EUR

977,323 (47,309)

[27, 28]

T2DM

Study-based diagnosis, medical records, or self-report

Case status^b

51% EUR, 28% EAS, 8% SAS, 7% AFR, 6% HIS

1,339,889 (180,834)

[29, 30]

CKD

Study-based, eGFR < 60 mL/min/1.73m²

Case status^b

 ~ 77% EUR

625,219 (64,164)

[31, 32]

LDL-C

Fasting or non-fasting. Adjusted for medication: LDL-C ÷ 0.7, TG ÷ 0.8

Per SD (mg/dL)

80% EUR, 9% EAS, 6% AFR, 3% HIS, 2% SAS

1,654,960

[33, 34]

HDL-C

[33, 35]

TG

[33, 36]

SBP

Mean of two seated measures taken a few moments apart

Per SD (mmHg)

100% EUR

317,756

[37,38,39]

DBP

317,756

[37, 38, 40]