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Table 2 Association analyses of sex transmitted infections and anti-Orthopoxvirus antibody responses among gay men aged ≤ 41 y

From: Unexpectedly higher levels of anti-orthopoxvirus neutralizing antibodies are observed among gay men than general adult population

 

Without STI (n= 275)

With STI (n = 20)

P value

Negative (n)

Positive (n)

Negative (n)

Positive (n)

H3 binding IgG

267

8

19

1

0.4732

A35 binding IgG

266

9

19

1

0.5100

A29 binding IgG

250

25

17

3

0.2921

B6 binding IgG

267

48

17

3

0.6377

E8 binding IgG

110

165

8

12

0.5879

M1 binding IgG

263

12

20

0

0.4235

Vaccinia binding IgG

274

1

19

1

0.1312

Neutralizing antibody

246

29

18

2

0.6480

  1. With STI, participants with diagnosed Syphilis, Gonorrhea, Chlamydia, genital herpes or genital warts during the 6 months before the enrollment. Without STI, participants without diagnosed STI during the 6 months prior to the enrollment. Participants who were not sure whether they had STIs or not during the 6 months prior to the enrollment were excluded from this analysis. PRNT50 ≥ 30 is classified as a positive neutralizing antibody response