Tissue | Ensembl gene ID | Gene symbol | CHR | BC | Depression | ||||
---|---|---|---|---|---|---|---|---|---|
Best.GWAS.ID | TWAS.Z | PBonferroni | Best.GWAS.ID | TWAS.Z | PBonferroni | ||||
Depression and overall breast cancer | |||||||||
 Whole Blood | ENSG00000137312.14 | FLOT1 | 6 | rs3130975 | -4.66 | 2.56 × 10–02 | rs3130557 | -6.15 | 6.10 × 10–06 |
 Uterus | ENSG00000225851.1 | HLA-S | 6 | rs3130975 | 4.30 | 4.07 × 10–02 | rs3130557 | 4.84 | 3.07 × 10–03 |
 Artery Coronary | ENSG00000247934.4 | . | 12 | rs7297051 | 7.41 | 4.87 × 10–10 | rs11049301 | -4.44 | 3.48 × 10–02 |
 Brain Cerebellum | ENSG00000168612.4 | ZSWIM1 | 20 | rs3746506 | -4.60 | 3.15 × 10–02 | rs9074 | 4.83 | 9.79 × 10–03 |
 Heart Left Ventricle | ENSG00000100351.16 | GRAP2 | 22 | rs17001868 | -4.87 | 6.69 × 10–03 | rs139915 | -4.50 | 3.93 × 10–02 |
Depression and ER + breast cancer | |||||||||
 Colon Transverse | ENSG00000137312.14 | FLOT1 | 6 | rs3130975 | -4.49 | 4.68 × 10–02 | rs3130557 | -7.49 | 4.31 × 10–10 |
 Artery Coronary | ENSG00000247934.4 | . | 12 | rs7297051 | 5.50 | 1.49 × 10–04 | rs11049301 | -4.44 | 3.48 × 10–02 |