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968 result(s) for 'alcohol' within BMC Medicine

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  2. Periconceptional folic acid prevents neural tube defects (NTDs), but it is uncertain whether there are benefits for offspring neurodevelopment arising from continued maternal folic acid supplementation beyond ...

    Authors: Helene McNulty, Mark Rollins, Tony Cassidy, Aoife Caffrey, Barry Marshall, James Dornan, Marian McLaughlin, Breige A. McNulty, Mary Ward, J. J. Strain, Anne M. Molloy, Diane J. Lees-Murdock, Colum P. Walsh and Kristina Pentieva
    Citation: BMC Medicine 2019 17:196
    Content type: Research article Published on:

  3. The human brain is complex and interconnected structurally. Brain connectome change is associated with Alzheimer’s disease (AD) and other neurodegenerative diseases. Genetics and genomics studies have identifi...

    Authors: Young Jae Woo, Panos Roussos, Vahram Haroutunian, Pavel Katsel, Samuel Gandy, Eric E. Schadt and Jun Zhu
    Citation: BMC Medicine 2020 18:23
    Content type: Research article Published on:

  4. Celiac disease remains a challenging condition because of a steady increase in knowledge tackling its pathophysiology, diagnosis, management, and possible therapeutic options.

    Authors: Giacomo Caio, Umberto Volta, Anna Sapone, Daniel A. Leffler, Roberto De Giorgio, Carlo Catassi and Alessio Fasano
    Citation: BMC Medicine 2019 17:142
    Content type: Review Published on:

  6. There is growing interest in evaluating differences in healthcare interventions across routinely collected demographic characteristics. However, individual subgroup analyses in randomized controlled trials are...

    Authors: Patrick Liu, John P. A. Ioannidis, Joseph S. Ross, Sanket S. Dhruva, Anita T. Luxkaranayagam, Vasilis Vasiliou and Joshua D. Wallach
    Citation: BMC Medicine 2019 17:188
    Content type: Research article Published on:

  7. Excessive gestational weight gain (GWG) leads to obstetric complications, maternal postpartum weight retention and an increased risk of offspring obesity. The GeliS study examines the effect of a lifestyle int...

    Authors: Julia Kunath, Julia Günther, Kathrin Rauh, Julia Hoffmann, Lynne Stecher, Eva Rosenfeld, Luzia Kick, Kurt Ulm and Hans Hauner
    Citation: BMC Medicine 2019 17:5
    Content type: Research article Published on:

  8. Despite an early response to platinum-based chemotherapy in advanced stage high-grade serous ovarian cancer (HGSOC), the majority of patients will relapse with drug-resistant disease. Aberrant epigenetic alter...

    Authors: Tushar Tomar, Nicolette G. Alkema, Leroy Schreuder, Gert Jan Meersma, Tim de Meyer, Wim van Criekinge, Harry G. Klip, Heidi Fiegl, Els van Nieuwenhuysen, Ignace Vergote, Martin Widschwendter, Ed Schuuring, Ate G. J. van der Zee, Steven de Jong and G. Bea A. Wisman
    Citation: BMC Medicine 2017 15:116
    Content type: Research article Published on:

  9. Reproductive events are associated with important physiologic changes, yet little is known about how reproductive factors influence long-term health in women. Our objective was to assess the relation of reprod...

    Authors: Melissa A. Merritt, Elio Riboli, Neil Murphy, Mai Kadi, Anne Tjønneland, Anja Olsen, Kim Overvad, Laure Dossus, Laureen Dartois, Françoise Clavel-Chapelon, Renée T. Fortner, Verena A. Katzke, Heiner Boeing, Antonia Trichopoulou, Pagona Lagiou, Dimitrios Trichopoulos…
    Citation: BMC Medicine 2015 13:252
    Content type: Research article Published on:

  10. Maternal metabolism during pregnancy is a major determinant of the intra-uterine environment and fetal outcomes. Herein, we characterize the maternal urinary metabolome throughout pregnancy to identify materna...

    Authors: Léa Maitre, Cristina M. Villanueva, Matthew R. Lewis, Jesús Ibarluzea, Loreto Santa-Marina, Martine Vrijheid, Jordi Sunyer, Muireann Coen and Mireille B. Toledano
    Citation: BMC Medicine 2016 14:177
    Content type: Research article Published on:

  11. Hypertension can be prevented by adopting healthy dietary patterns. Our aim was to assess the 4-year effect on blood pressure (BP) control of a randomized feeding trial promoting the traditional Mediterranean ...

    Authors: Estefania Toledo, Frank B Hu, Ramon Estruch, Pilar Buil-Cosiales, Dolores Corella, Jordi Salas-Salvadó, M Isabel Covas, Fernando Arós, Enrique Gómez-Gracia, Miquel Fiol, Jose Lapetra, Luis Serra-Majem, Xavier Pinto, Rosa M Lamuela-Raventós, Guillermo Saez, Mònica Bulló…
    Citation: BMC Medicine 2013 11:207
    Content type: Research article Published on:

  12. The influence of genetics and environment on the association of the plasma proteome with body mass index (BMI) and changes in BMI remains underexplored, and the links to other omics in these associations remai...

    Authors: Gabin Drouard, Fiona A. Hagenbeek, Alyce M. Whipp, René Pool, Jouke Jan Hottenga, Rick Jansen, Nikki Hubers, Aleksei Afonin, Gonneke Willemsen, Eco J. C. de Geus, Samuli Ripatti, Matti Pirinen, Katja M. Kanninen, Dorret I. Boomsma, Jenny van Dongen and Jaakko Kaprio
    Citation: BMC Medicine 2023 21:508
    Content type: Research article Published on:

  13. Major depression is one of the leading causes of disability worldwide, yet epidemiologic data are not available for many countries, particularly low- to middle-income countries. In this paper, we present data ...

    Authors: Evelyn Bromet, Laura Helena Andrade, Irving Hwang, Nancy A Sampson, Jordi Alonso, Giovanni de Girolamo, Ron de Graaf, Koen Demyttenaere, Chiyi Hu, Noboru Iwata, Aimee N Karam, Jagdish Kaur, Stanislav Kostyuchenko, Jean-Pierre Lépine, Daphna Levinson, Herbert Matschinger…
    Citation: BMC Medicine 2011 9:90
    Content type: Research article Published on:

  14. PARP inhibitors have shown promising clinical results in cancer patients carrying BRCA1/2 mutations. Their clinical efficacy could logically be influenced by PARP1 protein levels in patient tumors.

    Authors: Maud Marques, Marie-Claude Beauchamp, Hubert Fleury, Ido Laskov, Sun Qiang, Manuela Pelmus, Diane Provencher, Anne-Marie Mes-Masson, Walter H. Gotlieb and Michael Witcher
    Citation: BMC Medicine 2015 13:217
    Content type: Research article Published on:

  15. Serum retinol concentration determined by high-performance liquid chromatography (HPLC) is recommended by the World Health Organization to assess population vitamin A status. This assay is expensive, technical...

    Authors: Elise F Talsma, Hans Verhoef, Inge D Brouwer, Anne S Mburu-de Wagt, Paul JM Hulshof and Alida Melse-Boonstra
    Citation: BMC Medicine 2015 13:30
    Content type: Research article Published on:

  17. Cutaneous melanoma is the deadliest skin cancer, with an increasing incidence and mortality rate. Currently, staging of patients with primary melanoma is performed using histological biomarkers such as tumor t...

    Authors: Jasper Wouters, Miguel Vizoso, Anna Martinez-Cardus, F. Javier Carmona, Olivier Govaere, Teresa Laguna, Jesuchristopher Joseph, Peter Dynoodt, Claudia Aura, Mona Foth, Roy Cloots, Karin van den Hurk, Balazs Balint, Ian G. Murphy, Enda W. McDermott, Kieran Sheahan…
    Citation: BMC Medicine 2017 15:101
    Content type: Research article Published on:

  18. Specific phobia (SP) is a relatively common disorder associated with high levels of psychiatric comorbidity. Because of its early onset, SP may be a useful early marker of internalizing psychopathology, especi...

    Authors: Ymkje Anna de Vries, Ali Al-Hamzawi, Jordi Alonso, Guilherme Borges, Ronny Bruffaerts, Brendan Bunting, José Miguel Caldas-de-Almeida, Alfredo H. Cia, Giovanni De Girolamo, Rumyana V. Dinolova, Oluyomi Esan, Silvia Florescu, Oye Gureje, Josep Maria Haro, Chiyi Hu, Elie G. Karam…
    Citation: BMC Medicine 2019 17:101
    Content type: Research article Published on:
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