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  1. While the augmented incidence of diabetes after COVID-19 has been widely confirmed, controversial results are available on the risk of developing hypertension during the COVID-19 pandemic.

    Authors: Valentina Trimarco, Raffaele Izzo, Daniela Pacella, Ugo Trama, Maria Virginia Manzi, Angela Lombardi, Roberto Piccinocchi, Paola Gallo, Giovanni Esposito, Gaetano Piccinocchi, Maria Lembo, Carmine Morisco, Francesco Rozza, Gaetano Santulli and Bruno Trimarco
    Citation: BMC Medicine 2024 22:127
  2. Highlighted by the rise of COVID-19, climate change, and conflict, socially vulnerable populations are least resilient to disaster. In infectious disease management, mathematical models are a commonly used too...

    Authors: Megan Naidoo, Whitney Shephard, Innocensia Kambewe, Nokuthula Mtshali, Sky Cope, Felipe Alves Rubio and Davide Rasella
    Citation: BMC Medicine 2024 22:125
  3. Several neurological manifestations shortly after a receipt of coronavirus infectious disease 2019 (COVID-19) vaccine have been described in the recent case reports. Among those, we sought to evaluate the risk...

    Authors: Ju Hwan Kim, Dongwon Yoon, Hwa Yeon Ko, Kyungyeon Jung, Jun-Sang Sunwoo, Won Chul Shin, Jung-Ick Byun and Ju-Young Shin
    Citation: BMC Medicine 2024 22:123
  4. Patients with fibro-calcific aortic valve disease (FCAVD) have lipid depositions in their aortic valve that engender a proinflammatory impetus toward fibrosis and calcification and ultimately valve leaflet ste...

    Authors: Dohee Yoon, Bongkun Choi, Ji-Eun Kim, Eun-Young Kim, Soo-Hyun Chung, Hyo-Jin Min, Yoolim Sung, Eun-Ju Chang and Jae-Kwan Song
    Citation: BMC Medicine 2024 22:122
  5. Socio-emotional impairments are among the diagnostic criteria for autism spectrum disorder (ASD), but the actual knowledge has substantiated both altered and intact emotional prosodies recognition. Here, a Bay...

    Authors: Mathilde Marie Duville, Luz María Alonso-Valerdi and David I. Ibarra-Zarate
    Citation: BMC Medicine 2024 22:121
  6. Numerous observational studies have highlighted associations of genetic predisposition of head and neck squamous cell carcinoma (HNSCC) with diverse risk factors, but these findings are constrained by design l...

    Authors: Young Chan Lee, Sang-Hyuk Jung, Manu Shivakumar, Soojin Cha, Woong-Yang Park, Hong-Hee Won, Young-Gyu Eun, Penn Medicine Biobank and Dokyoon Kim
    Citation: BMC Medicine 2024 22:120
  7. Intravenous leiomyomatosis (IVL), pulmonary benign metastatic leiomyomatosis (PBML), and leiomyomatosis peritonealis disseminata (LPD) are leiomyomas with special growth patterns and high postoperative recurre...

    Authors: Guorui Zhang, Rong Fan, Hua Yang, Hao Su, Xin Yu, Yutong Wang, Fengzhi Feng and Lan Zhu
    Citation: BMC Medicine 2024 22:119
  8. Few previous studies have assessed overall morbidity at the individual level with respect to future risk of hip fracture. The aim of this register-based cohort study was to examine the association between morb...

    Authors: Siri Marie Solbakken, Haakon Eduard Meyer, Cecilie Dahl, Trine Elisabeth Finnes, Vidar Hjellvik, Christopher Sivert Nielsen, Tone Kristin Omsland, Hein Stigum and Kristin Holvik
    Citation: BMC Medicine 2024 22:118
  9. Paxlovid has been shown to be effective in reducing mortality and hospitalization rates in patients with coronavirus disease 2019 (COVID-19). It is not known whether Paxlovid can reduce the risk of cardiovascu...

    Authors: Weijie Wang, Yu-Hsun Wang, Ching-Hua Huang, Tsung-Hsueh Hsieh, Gema Hernández Ibarburu and James Cheng-Chung Wei
    Citation: BMC Medicine 2024 22:117
  10. Experiences during childhood and adolescence have enduring impacts on physical and mental well-being, overall quality of life, and socioeconomic status throughout one’s lifetime. This underscores the importanc...

    Authors: Chengchen Duan, Liu Liu, Tianyi Wang, Guanru Wang, Zhishen Jiang, Honglin Li, Gaowei Zhang, Li Ye, Chunjie Li and Yubin Cao
    Citation: BMC Medicine 2024 22:116
  11. The global dementia prevalence is surging, necessitating research into contributing factors. We aimed to investigate the association between metabolic syndrome (MetS), its components, serum uric acid (SUA) lev...

    Authors: Tara SR Chen, Ning-Ning Mi, Hubert Yuenhei Lao, Chen-Yu Wang, Wai Leung Ambrose Lo, Yu-Rong Mao, Yan Tang, Zhong Pei, Jin-Qiu Yuan and Dong-Feng Huang
    Citation: BMC Medicine 2024 22:115
  12. Type 2 diabetes (T2D) is associated with an increased risk of premature death. Whether multifactorial risk factor modification could attenuate T2D-related excess risk of death is unclear. We aimed to examine t...

    Authors: Bin Wang, Yanqi Fu, Xiao Tan, Ningjian Wang, Lu Qi and Yingli Lu
    Citation: BMC Medicine 2024 22:114
  13. In post-stroke atrial fibrillation (AF) patients who have indications for both oral anticoagulant (OAC) and antiplatelet agent (AP), e.g., those with carotid artery stenosis, there is debate over the best anti...

    Authors: Chuan-Tsai Tsai, Yi-Hsin Chan, Jo-Nan Liao, Tzeng-Ji Chen, Gregory Y. H. Lip, Shih-Ann Chen and Tze-Fan Chao
    Citation: BMC Medicine 2024 22:113
  14. The transitivity assumption is the cornerstone of network meta-analysis (NMA). Violating transitivity compromises the credibility of the indirect estimates and, by extent, the estimated treatment effects of th...

    Authors: Loukia M. Spineli, Chrysostomos Kalyvas, Juan Jose Yepes-Nuñez, Andrés Mauricio García-Sierra, Diana C. Rivera-Pinzón, Svenja E. Seide and Katerina Papadimitropoulou
    Citation: BMC Medicine 2024 22:112
  15. Previous randomized controlled trials (RCTs) suggested that gut microbiota-based therapies may be effective in treating autoimmune diseases, but a systematic summary is lacking.

    Authors: Liuting Zeng, Kailin Yang, Qi He, Xiaofei Zhu, Zhiyong Long, Yang Wu, Junpeng Chen, Yuwei Li, Jinsong Zeng, Ge Cui, Wang Xiang, Wensa Hao and Lingyun Sun
    Citation: BMC Medicine 2024 22:110
  16. Omega-3 polyunsaturated fatty acids (n-3 PUFA) have been suggested as a cognitive enhancing agent, though their effect is doubtful. We aimed to examine the effect of n-3 PUFA on the cognitive function of middl...

    Authors: Seung Wan Suh, Eunji Lim, Suh-Yuhn Burm, Hyungji Lee, Jong Bin Bae, Ji Won Han and Ki Woong Kim
    Citation: BMC Medicine 2024 22:109
  17. The emergence of new SARS-CoV-2 variants and the waning of immunity raise concerns about vaccine effectiveness and protection against COVID-19. While antibody response has been shown to correlate with the risk...

    Authors: Carla Martín Pérez, Ruth Aguilar, Alfons Jiménez, Gemma Salmerón, Mar Canyelles, Rocío Rubio, Marta Vidal, Inocencia Cuamba, Diana Barrios, Natalia Díaz, Rebeca Santano, Pau Serra, Pere Santamaria, Luis Izquierdo, Antoni Trilla, Anna Vilella…
    Citation: BMC Medicine 2024 22:103
  18. Diabetes patients are at higher risk for mortality than the general population; however, little is known about whether the excess mortality risk associated with diabetes could be mitigated or nullified via con...

    Authors: Jian Zhou, Xuan Wang, Rui Tang, Minghao Kou, Hao Ma, Xiang Li, Yoriko Heianza, Vivian Fonseca and Lu Qi
    Citation: BMC Medicine 2024 22:108
  19. Classical Hodgkin lymphoma (cHL) is a highly curable disease, while novel therapy is needed for refractory or relapsed (R/R) patients. This phase II trial aimed to evaluate the role of camrelizumab plus gemcit...

    Authors: Yanfei Liu, Lingyan Ping, Yuqin Song, Yongjing Tang, Wen Zheng, Weiping Liu, Zhitao Ying, Chen Zhang, Meng Wu, Feier Feng, Ningjing Lin, Meifeng Tu, Jun Zhu and Yan Xie
    Citation: BMC Medicine 2024 22:107
  20. The relaxation of the “zero-COVID” policy on Dec. 7, 2022, in China posed a major public health threat recently. Complete blood count test was discovered to have complicated relationships with COVID-19 after t...

    Authors: Yifei Lin, Yong Yang, Nanyan Xiang, Le Wang, Tao Zheng, Xuejun Zhuo, Rui Shi, Xiaoyi Su, Yan Liu, Ga Liao, Liang Du and Jin Huang
    Citation: BMC Medicine 2024 22:105
  21. The specific microbiota and associated metabolites linked to non-alcoholic fatty liver disease (NAFLD) are still controversial. Thus, we aimed to understand how the core gut microbiota and metabolites impact N...

    Authors: Fangfang Zeng, Xin Su, Xinxiu Liang, Minqi Liao, Haili Zhong, Jinjian Xu, Wanglong Gou, Xiangzhou Zhang, Luqi Shen, Ju-Sheng Zheng and Yu-ming Chen
    Citation: BMC Medicine 2024 22:104
  22. Empirical evidence suggests that lack of blinding may be associated with biased estimates of treatment benefit in randomized controlled trials, but the influence on medication-related harms is not well-recogni...

    Authors: Chang Xu, Fengying Zhang, Suhail A. R. Doi, Luis Furuya-Kanamori, Lifeng Lin, Haitao Chu, Xi Yang, Sheyu Li, Liliane Zorzela, Su Golder, Yoon Loke and Sunita Vohra
    Citation: BMC Medicine 2024 22:83
  23. Effectively managing the coexistence of both diabetes and disability necessitates substantial effort. Whether disability onset affects adherence to type 2 diabetes medication remains unclear. This study invest...

    Authors: Szu-Han Chen, Miaw-Chwen Lee and Christy Pu
    Citation: BMC Medicine 2024 22:102
  24. Non-alcoholic fatty liver disease (NAFLD) and metabolic-associated fatty liver disease (MAFLD) shares common pathophysiological mechanisms with type 2 diabetes, making them significant risk factors for type 2 ...

    Authors: Limin Cao, Yu An, Huiyuan Liu, Jinguo Jiang, Wenqi Liu, Yuhan Zhou, Mengyuan Shi, Wei Dai, Yanling Lv, Yuhong Zhao, Yanhui Lu, Liangkai Chen and Yang Xia
    Citation: BMC Medicine 2024 22:101
  25. In 2021, whilst societies were emerging from major social restrictions during the SARS-CoV-2 pandemic, the UK government instigated an Events Research Programme to examine the risk of COVID-19 transmission fro...

    Authors: Ian J. Douglas, Jerlyn Peh, Kathryn E. Mansfield, Anna Trelfa, Tom Fowler, Matthew Boulter, Paul Cleary, Jenifer Smith and W. John Edmunds
    Citation: BMC Medicine 2024 22:100
  26. The increasing prevalence of gestational diabetes mellitus (GDM) is a major challenge, particularly in rural areas of China where control rates are suboptimal. This study aimed to evaluate the effectiveness of...

    Authors: Tingting Xu, Qing Xia, Xiaozhen Lai, Kun He, Dazhi Fan, Liangkun Ma and Hai Fang
    Citation: BMC Medicine 2024 22:98
  27. Carbohydrates have been implicated in colorectal cancer (CRC) risk, but the specific impact of carbohydrate quality and quantity on CRC susceptibility in US populations remains unclear.

    Authors: Yi Xiao, Ling Xiang, Yahui Jiang, Yunhao Tang, Haitao Gu, Yaxu Wang and Linglong Peng
    Citation: BMC Medicine 2024 22:97
  28. There is a lack of effective therapeutic strategies for amyotrophic lateral sclerosis (ALS); therefore, drug repurposing might provide a rapid approach to meet the urgent need for treatment.

    Authors: Qing-Qing Duan, Han Wang, Wei-Ming Su, Xiao-Jing Gu, Xiao-Fei Shen, Zheng Jiang, Yan-Ling Ren, Bei Cao, Guo-Bo Li, Yi Wang and Yong-Ping Chen
    Citation: BMC Medicine 2024 22:96
  29. The key role of thrombospondin 1 (THBS1) in the pathogenesis of acute-on-chronic liver failure (ACLF) is unclear. Here, we present a transcriptome approach to evaluate THBS1 as a potential biomarker in ACLF di...

    Authors: Hozeifa Mohamed Hassan, Xi Liang, Jiaojiao Xin, Yingyan Lu, Qun Cai, Dongyan Shi, Keke Ren, Jun Li, Qi Chen, Jiang Li, Peng Li, Beibei Guo, Hui Yang, Jinjin Luo, Heng Yao, Xingping Zhou…
    Citation: BMC Medicine 2024 22:95
  30. There is a high prevalence of autoimmune conditions in women specially in the reproductive years; thus, the association with adverse pregnancy outcomes has been widely studied. However, few autoimmune conditio...

    Authors: Megha Singh, Steven Wambua, Siang Ing Lee, Kelvin Okoth, Zhaonan Wang, Fathima Fazla Ahamed Fayaz, Kelly-Ann Eastwood, Catherine Nelson-Piercy, John A. Reynolds, Krishnarajah Nirantharakumar and Francesca Crowe
    Citation: BMC Medicine 2024 22:94
  31. Cardiovascular disease (CVD) caused by air pollution poses a considerable burden on public health. We aim to examine whether lifestyle factors mediate the associations of air pollutant exposure with the risk o...

    Authors: Xiangming Hu, Luke D. Knibbs, Yingling Zhou, Yanqiu Ou, Guang-Hui Dong and Haojian Dong
    Citation: BMC Medicine 2024 22:93
  32. Autism spectrum disorder (ASD) and attention-deficit/hyperactivity disorder (ADHD) are neurodevelopmental disorders with overlapping behavioral features and genetic etiology. While brain cortical thickness (CT...

    Authors: Wanfang You, Qian Li, Lizhou Chen, Ning He, Yuanyuan Li, Fenghua Long, Yaxuan Wang, Yufei Chen, Robert K. McNamara, John A. Sweeney, Melissa P. DelBello, Qiyong Gong and Fei Li
    Citation: BMC Medicine 2024 22:92
  33. Epilepsy, characterized by recurrent unprovoked seizures, poses significant challenges to affected individuals globally. While several established risk factors for epilepsy exist, the association with cigarett...

    Authors: Yerin Kang, Sieun Kim, Yunah Jung, Dai Sik Ko, Hyun-Woo Kim, Jung-Pil Yoon, Sunghwan Cho, Tae-Jin Song, Kihun Kim, Eunjeong Son and Yun Hak Kim
    Citation: BMC Medicine 2024 22:91
  34. While circulating metabolites have been increasingly linked to cancer risk, the causality underlying these associations remains largely uninterrogated.

    Authors: Yaxin Chen, Yufang Xie, Hang Ci, Zhengpei Cheng, Yongjie Kuang, Shuqing Li, Gang Wang, Yawen Qi, Jun Tang, Dan Liu, Weimin Li and Yaohua Yang
    Citation: BMC Medicine 2024 22:90
  35. Black men have higher prostate-specific antigen (PSA) levels and higher prostate cancer incidence and mortality than White men, while Asian men tend to have lower prostate cancer incidence and mortality than W...

    Authors: Liz Down, Melissa Barlow, Sarah E. R. Bailey, Luke T. A. Mounce, Samuel W. D. Merriel, Jessica Watson and Tanimola Martins
    Citation: BMC Medicine 2024 22:82
  36. Dairy contains a complex mixture of lipids, proteins, and micronutrients. Whether habitual dairy consumption is associated with health benefits is not well established. Since dairy is high in nutrients that ar...

    Authors: Ellen A. Struijk, Teresa T. Fung, Fernando Rodriguez-Artalejo, Heike A. Bischoff-Ferrari, Walter C. Willett and Esther Lopez-Garcia
    Citation: BMC Medicine 2024 22:89
  37. Peer support for mental health is recommended across international policy guidance and provision. Our systematic umbrella review summarises evidence on the effectiveness, implementation, and experiences of pai...

    Authors: Ruth E. Cooper, Katherine R. K. Saunders, Anna Greenburgh, Prisha Shah, Rebecca Appleton, Karen Machin, Tamar Jeynes, Phoebe Barnett, Sophie M. Allan, Jessica Griffiths, Ruth Stuart, Lizzie Mitchell, Beverley Chipp, Stephen Jeffreys, Brynmor Lloyd-Evans, Alan Simpson…
    Citation: BMC Medicine 2024 22:72
  38. The risk of incident atrial fibrillation (AF) among breast cancer survivors, especially for younger women, and cancer treatment effects on the association remain unclear. This study aimed to investigate the ri...

    Authors: Yong-Moon Mark Park, Wonyoung Jung, Yohwan Yeo, Sang Hyun Park, Michael G. Fradley, Sindhu J. Malapati, Tushar Tarun, Vinay Raj, Hong Seok Lee, Tasneem Z. Naqvi, Ronda S. Henry-Tillman, Jawahar L. Mehta, Mario Schootman, Benjamin C. Amick III, Kyungdo Han and Dong Wook Shin
    Citation: BMC Medicine 2024 22:88
  39. Myocardial bridging (MB) is common in patients with hypertrophic cardiomyopathy (HCM). There are sparse data on the impact of MB on myocardial fibrosis in HCM. This study was designed to evaluate the relations...

    Authors: Changpeng Song, Shengwei Wang, Xinli Guo, Manyun Huang, Xinxin Zheng, Jie Lu, Keshan Ji, Shihua Zhao, Jingang Cui, Shuiyun Wang and Xiaohong Huang
    Citation: BMC Medicine 2024 22:86
  40. For patients with steroid-refractory acute graft-versus-host disease (SR-aGVHD), effective second-line regimens are urgently needed. Mesenchymal stromal cells (MSCs) have been used as salvage regimens for SR-a...

    Authors: Haixia Fu, Xueyan Sun, Ren Lin, Yu Wang, Li Xuan, Han Yao, Yuanyuan Zhang, Xiaodong Mo, Meng lv, Fengmei Zheng, Jun Kong, Fengrong Wang, Chenhua Yan, Tingting Han, Huan Chen, Yao Chen…
    Citation: BMC Medicine 2024 22:85
  41. It has been repeatedly shown that men infected by SARS-CoV-2 face a twofold higher likelihood of dying, being hospitalized or admitted to the intensive care unit compared to women, despite taking into account ...

    Authors: Evangelia Elenis, Helena Kopp Kallner, Maria A. Karalexi, David Hägg, Marie Linder, Katja Fall, Fotios C. Papadopoulos and Alkistis Skalkidou
    Citation: BMC Medicine 2024 22:84
  42. Dysbiosis of the gut microbiome is frequent in the intensive care unit (ICU), potentially leading to a heightened risk of nosocomial infections. Enhancing the gut microbiome has been proposed as a strategic ap...

    Authors: Vinod K. Gupta, Sanu Rajendraprasad, Mahmut Ozkan, Dhanya Ramachandran, Sumera Ahmad, Johan S. Bakken, Krzysztof Laudanski, Ognjen Gajic, Brent Bauer, Simon Zec, David W. Freeman, Sahil Khanna, Aditya Shah, Joseph H. Skalski, Jaeyun Sung and Lioudmila V. Karnatovskaia
    Citation: BMC Medicine 2024 22:80
  43. The immunity induced by primary vaccination is effective against COVID-19; however, booster vaccines are needed to maintain vaccine-induced immunity and improve protection against emerging variants. Heterologo...

    Authors: Saeed Erfanpoor, Seyed Reza Banihashemi, Ladan Mokhbaeralsafa, Saeed Kalantari, Ali Es-haghi, Mojtaba Nofeli, Ali Rezaei Mokarram, Fariba Sadeghi, Monireh Hajimoradi, Seyad Hossein Razaz, Maryam Taghdiri, Mohsen Lotfi, Akbar Khorasani, Akram Ansarifar, Safdar Masoumi, Arash Mohazzab…
    Citation: BMC Medicine 2024 22:78
  44. The coexistence of hepatitis B surface antigen (HBsAg) and hepatitis B surface antibody (HBsAb) represents an uncommon serological pattern observed in patients with hepatitis B virus (HBV) infection, and its u...

    Authors: Yingping Gu, Shuangjie Li, Zhenzhen Yao, Xin Lai, Meng Yang, Yi Xu and Songxu Peng
    Citation: BMC Medicine 2024 22:77
  45. To combat the opioid crisis, interventions targeting the opioid prescribing behaviour of physicians involved in the management of patients with chronic non-cancer pain (CNCP) have been introduced in clinical s...

    Authors: Katya Peri, Lucy Honeycutt, Erica Wennberg, Sarah B. Windle, Kristian B. Filion, Genevieve Gore, Irina Kudrina, Elena Paraskevopoulos, Areesha Moiz, Marc O. Martel and Mark J. Eisenberg
    Citation: BMC Medicine 2024 22:76