Table 1 Multivariate Cox regression analysis of the eight-gene signature for predicting relapse-free survival in cancer patients
Variable | Hazard ratio | 95% CI | P-value |
|---|---|---|---|
Lung cancer (n = 71) | |||
Eight-gene signature | 5.33 | 1.76 to 16.1 | 0.003 |
Age | 1.05 | 1.00 to 1.11 | 0.060 |
Gender (Male vs Female) | 1.33 | 0.48 to 3.68 | 0. 581 |
Stage (1 vs 2) | 2.69 | 1.12 to 6.45 | 0.027 |
Histology Type | 1.45 | 0.56 to 3.73 | 0.443 |
Breast cancer (n = 462) | |||
Eight-gene signature | 1.81 | 1.19 to 2.76 | 0.006 |
Age (>50 vs ≦50) | 1.04 | 0.70 to 1.56 | 0.834 |
Clinical nodal status (positive vs negative) | 2.47 | 1.45 to 4.18 | 0.0008 |
Clinical tumor stage (T3 or T4 vs T1 or T2) | 1.80 | 1.20 to 2.70 | 0. 004 |
ER status (IHC positive vs negative) | 0.44 | 0.29 to 0.67 | 0.0001 |