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Table 1 Number of VDR binding sites

From: Vitamin D receptor ChIP-seq in primary CD4+ cells: relationship to serum 25-hydroxyvitamin D levels and autoimmune disease

Sample/group

25-OH D

Total

Downstream

Exons

Intergenic

Introns

Up and downstream

Upstream

UTR

  

Number

%

High 25-hydroxyvitamin D

≥75

13,054

5.3

4.0

32.8

28.4

4.7

14.6

10.2

Low 25-hydroxyvitamin D

<75

1,526

3.7

4.8

36.5

18.6

4.3

18.8

13.3

1_VDR

80

3,073

5.2

3.9

37.9

24.0

4.7

13.8

10.5

2_VDR

107

7,118

5.6

4.5

28.2

26.3

5.1

17.0

13.2

3_VDR

76

5,290

5.4

3.5

36.8

29.1

4.1

12.9

8.3

4_VDR

85

3,059

5.1

4.0

37.3

22.3

4.7

15.6

11.0

5_VDR

75

4,051

4.6

4.8

33.0

21.5

5.3

18.8

12.1

HB

29

1,021

3.5

5.7

27.4

16.9

5.6

24.1

17.0

PD

32

200

1.0

3.0

61.7

21.4

0.5

7.0

5.5

SP

34

610

3.2

4.5

38.7

18.8

3.7

18.3

13.0

SR

22

573

3.5

4.9

39.7

17.7

4.0

18.5

11.7

r

 

0.92

0.82

−0.22

−0.40

0.79

0.44

−0.14

−0.05

P

 

0.0005

0.0068

0.5746

0.2822

0.0115

0.2401

0.7163

0.891

  1. The number of VDR binding sites at FDR <0.1%. 25-hydroxyvitamin D (25(OH)D) levels are shown in nM. Correlations are shown between 25(OH)D and the number of binding sites. VDR, vitamin D receptor.