Reason for Discontinuation n (%) | Study 1 (n = 339) | Study 2 (n = 346) | Study 3 (n = 548) | Study 4 (n = 394) | Total (N = 1627) |
---|---|---|---|---|---|
Overall Discontinuation | 161(47.5) | 190(54.9) | 268(48.9) | 247(62.7) | 866(53.2) |
Poor Response or Worsening | 67(41.6) | 78(41.0) | 99(36.9) | 71(28.7) | 315(36.4) |
Intolerability to Medication | 19(11.8) | 16(8.4) | 31(11.6) | 40(16.2) | 106(12.2) |
Other Reasons* | 75(46.6) | 96(50.5) | 138(51.5) | 136(55.1) | 445(51.4) |