Table 3 OXTR promoter CpG methylation status in peripheral blood mononuclear cells (PBMCs) and cortex samples of males
From: Genomic and epigenetic evidence for oxytocin receptor deficiency in autism
Site | AutD cases (95%CI), (n = 10) | Controls (95%CI), (n = 10) | t Test |
|---|---|---|---|
PBMCs: | Â | Â | Â |
-860 | 41.0% (28.4 to 53.7) | 13.8% (6.6 to 21.0) | 0.0008 |
-901 | 48.1% (33.6 to 62.7) | 36.9% (19.1 to 54.7) | 0.3153 |
-924 | 71.1% (59.4 to 82.8) | 59.3% (40.8 to 77.8) | 0.2604 |
-934 | 58.7% (39.4 to 78.1) | 19.8% (3.2 to 36.4) | 0.0029 |
-959 | 48.6% (39.5 to 57.6) | 41.7% (27.5 to 55.9) | 0.3522 |
Cortex: | Â | Â | Â |
-860 | 38.8% (5.4 to 72.2) | 14.9% (3.6 to 26.2) | 0.1208 |
-901 | 47.1% (13.1 to 81.2) | 13.3% (3.6 to 23.0) | 0.0508 |
-924 | 64.3% (30.6 to 98.0) | 26.6% (7.2 to 46.1) | 0.0375 |
-934 | 61.0% (24.4 to 97.5) | 19.4% (1.1 to 37.7) | 0.0320 |
-959 | 20.5% (8.0 to 32.9) | 19.4% (1.1 to 37.7) | 0.9032 |