Table 2 Final analysis
From: A perspective on SIDS pathogenesis. The hypotheses: plausibility and evidence
Hypothesis | 1. Does the hypothesis take into account the key pathological findings? | 2. Is the hypothesis congruent with the key epidemiological risk factors? | 3. Does the hypothesis link 1 and 2? |
|---|---|---|---|
Brainstem control of respiratory function | No | No | No |
Brainstem control of cardiac function | Partly | Yes | Partly |
Respiratory obstruction/unintentional asphyxia | No | Partly | No |
Common bacterial toxins | Yes | Yes | Yes |
Shock including anaphylaxis | Yes | Yes | Partly |
Thermal stress | Partly | Yes | No |
Diaphragm failure | Partly | Yes | Partly |
CO2 rebreathing | No | No | No |
toxic gases emitted from fungally colonized mattresses | No | No | No |
Abuse | No | No | No |