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Table 6 Association between kidney disease and grade of hypertension among all 454 Tanzanian adult study participants and in each of the three study groups

From: Hypertension, kidney disease, HIV and antiretroviral therapy among Tanzanian adults: a cross-sectional study

Among 454 Tanzanian adult study participants

 

Normal

Prehypertension

Hypertension Grade 1

Hypertension Grade 2

P-value for trend

(number = 184)

(number = 194)

(number = 60)

(number = 16)

Kidney Disease a

44 (23.9%)

58 (29.9%)

40 (66.7%)

11 (68.8%)

<0.001

Microalbuminuria

33 (17.9%)

49 (25.3%)

40 (66.7%)

10 (62.5%)

<0.001

eGFR <60

16 (8.7%)

19 (9.8%)

14 (23.3%)

6 (37.5%)

<0.001

Among 153 HIV-negative adults (controls)

 

Normal

Prehypertension

Hypertension Grade 1

Hypertension Grade 2

P-value for trend

(number = 66)

(number = 62)

(number = 20)

(number = 5)

Kidney Disease

8 (12.1%)

15 (24.2%)

13 (65.0%)

3 (60.0%)

<0.001

Microalbuminuria

4 (6.1%)

12 (19.4%)

13 (65.0%)

2 (40.0%)

<0.001

eGFR <60

5 (7.6%)

6 (9.7%)

6 (30.0%)

3 (60.0%)

<0.001

Among 151 HIV-infected, ART-naive adults

 

Normal

Prehypertension

Hypertension Grade 1

Hypertension Grade 2

P -value for trend

(number = 69)

(number = 74)

(number = 7)

(number = 1)

Kidney Disease

22 (31.9%)

24 (32.4%)

5 (71.4%)

1 (100%)

0.11

Microalbuminuria

16 (23.2%)

21 (28.4%)

5 (71.4%)

1 (100%)

0.02

eGFR <60

8 (11.6%)

9 (12.2%)

2 (28.6%)

0

0.53

Among 150 HIV-infected adults on ART

 

Normal

Prehypertension

Hypertension Grade 1

Hypertension Grade 2

P -value for trend

(number = 49)

(number = 58)

(number = 33)

(number = 10)

Kidney Disease

14 (28.6%)

19 (32.8%)

22 (66.7%)

7 (70.0%)

<0.001

Microalbuminuria

13 (26.5%)

16 (27.6%)

22 (66.7%)

7 (70.0%)

<0.001

eGFR <60

3 (6.1%)

4 (6.9%)

6 (18.2%)

3 (30.0%)

0.01

  1. aThe primary kidney disease outcome: defined as microalbuminuria and/or eGFR <60 mL/min. ART, antiretroviral therapy; eGFR, estimated glomerular filtration rate.