Baseline characteristics | Mean (SD) or % (number) | ||
---|---|---|---|
Intervention arm | Control arm | Total | |
Patient baseline characteristics | |||
Age (years) | 70 (9.4) | 67 (13.3) | 69 (11.5) |
Sex (female) | 59% (21) | 62% (20) | 61% (41) |
Lives alone | 34% (12) | 28% (9) | 31% (21) |
Cancer site (primary): | Â | Â | Â |
Lung | 45% (16) | 54% (17) | 49% (33) |
Breast | 25% (9) | 13% (4) | 19% (13) |
Rectal/bowel | 6% (2) | 6% (2) | 6% (4) |
Prostate | 6% (2) | 3% (1) | 4% (3) |
Lymphoma | 3% (1) | 6% (2) | 4% (3) |
Mesothelioma | 3% (1) | 6% (2) | 4% (3) |
Gastro-oesophageal junction | 3% (1) | 3% (1) | 3% (2) |
Renal | 3% (1) | 3% (1) | 3% (2) |
Endometrial | 0% (0) | 3% (1) | 2% (1) |
Hepatocellular | 3% (1) | 0% (0) | 2% (1) |
Bladder | 0% (0) | 3% (1) | 2% (1) |
Unknown primary | 3% (1) | 0% (0) | 2% (1) |
Charlson Co-Morbidity Index (0 to 9)a | 6.34 (2.30) | 5.63 (2.14) | 6.00 (2.24) |
Australia-modified Karnofsky Performance Scale (0 to 100)b,c | 71.1 (12.6) | 74.1 (14.8) | 72.5 (13.6) |
Modified Borg: breathlessness at rest (0 to 10)a | 1.69 (1.09) | 1.39 (1.77) | 1.55 (1.45) |
Modified Borg: breathlessness on exertion (0 to 10)a | 5.27 (2.18) | 5.13 (2.21) | 5.20 (2.18) |
NRS worst breathlessness 24 hours (0 to 10)a | 4.97 (2.46) | 4.19 (2.28) | 4.60 (2.39) |
NRS breathlessness now (0 to 10)a | 2.29 (1.74) | 1.81 (1.38) | 2.06 (1.59) |
NRS average breathlessness 24 hours (0 to 10)a | 3.83 (1.67) | 3.38 (1.93) | 3.61 (1.80) |
NRS distress due to breathlessness (0 to 10)a | 5.17 (2.81) | 4.94 (2.84) | 5.06 (2.81) |
Anxiety score (HADS) (0 to 21)a | 6.97 (4.01) | 8.09 (3.31) | 7.52 (3.70) |
Depression score (HADS) (0 to 21)a | 6.61 (2.73) | 5.91 (2.99) | 6.26 (2.87) |
Anxiety (HADS)a: | Â | Â | Â |
Normal (0 to 7) | 55% (18) | 53% (17) | 54% (35) |
Mild (8 to 10; possible clinical disorder) | 27% (9) | 19% (6) | 23% (15) |
Moderate (11 to 14; probable clinical disorder) | 15% (5) | 25% (8) | 20% (13) |
Severe (15 to 21; probable clinical disorder) | 3% (1) | 3% (1) | 3% (2) |
Depression (HADS)a: | Â | Â | Â |
Normal (0 to 7) | 70% (23) | 78% (25) | 74% (48) |
Mild (8 to 10; possible clinical disorder) | 21% (7) | 9% (3) | 15% (10) |
Moderate (11 to 14; probable clinical disorder) | 9% (3) | 13% (4) | 11% (7) |
Severe (15 to 21; probable clinical disorder) | 0% (0) | 0% (0) | 0% (0) |
CRQ dyspnoea score (1 to 7)b | 3.42 (0.99) | 3.39 (0.98) | 3.41 (0.98) |
CRQ fatigue score (1 to 7)b | 3.38 (1.33) | 3.20 (1.07) | 3.29 (1.20) |
CRQ emotional function score (1 to 7)b | 4.43 (1.02) | 4.46 (1.30) | 4.35 (1.06) |
CRQ mastery score (1 to 7)b | 4.57 (1.15) | 4.46 (1.30) | 4.52 (1.22) |
Number of respondents (patients) | 33-35 | 32 | 65-67 |
Carer baseline characteristics | |||
Carer age (years) | 65.6 (13.4) | 63.5 (12.2) | 64.6 (12.7) |
Carer sex (female) | 70% (14) | 67% (14) | 68% (28) |
Carer employment status: | Â | Â | Â |
Employed - full time | 11% (2) | 24% (5) | 18% (7) |
Employed - part time | 22% (4) | 5% (1) | 13% (5) |
Retired | 61% (11) | 57% (12) | 59% (23) |
Other (e.g. unemployed due to illness/student) | 6% (1) | 14% (3) | 10% (4) |
NRS carer distress due to patient breathlessness (0 to 10)a | 3.56 (2.44) | 3.86 (2.82) | 3.72 (2.62) |
Carer anxiety score (HADS) (0 to 21)a | 7.89 (5.33) | 6.76 (3.59) | 7.28 (4.45) |
Carer depression score (HADS) (0 to 21)a | 3.39 (3.91) | 4.29 (2.93) | 3.87 (3.40) |
Carer anxiety (HADS)a: | Â | Â | Â |
Normal (0 to 7) | 44% (8) | 57% (12) | 51% (20) |
Mild (8 to 10; possible clinical disorder) | 17% (3) | 24% (5) | 21% (8) |
Moderate (11 to 14; probable clinical disorder) | 28% (5) | 19% (4) | 23% (9) |
Severe (15 to 21; probable clinical disorder) | 11% (2) | 0% (0) | 5% (2) |
Carer depression (HADS)a: | Â | Â | Â |
Normal (0 to 7) | 78% (14) | 76% (16) | 77% (30) |
Mild (8 to 10; possible clinical disorder) | 22% (4) | 19% (4) | 20% (8) |
Moderate (11 to 14; probable clinical disorder) | 0% (0) | 5% (1) | 3% (1) |
Severe (15 to 21; probable clinical disorder) | 0% (0) | 0% (0) | 0% (0) |
Number of respondents (carers) | 18-20 | 19-21 | 39-41 |
No carer/no carer interview | 43% (15) | 34% (11) | 39% (26) |