From: Prevalence of genetic variants of keratins 8 and 18 in patients with drug-induced liver injury
 | Subgroup (#) |  | K8 G62C | K8 I63V | K8 A333A | K8 R341H | K8 V380I | K8 G434S | K8 V480I | Totala |
---|---|---|---|---|---|---|---|---|---|---|
# | 11/800 | 9/800 | 15/800 | 40/800 | 3/800 | 10/800 | 7/800 | 86/800 | ||
% | 1.4 | 1.1 | 1.9 | 5.0 | 0.4 | 1.3 | 0.9 | 10.8 | ||
DILI | Caucasian (577) | # | 10b | 8 | 0 | 27b | 3 | 0 | 3 | 54 |
% | 1.7 | 1.4 | 0 | 4.7 | 0.5 | 0 | 0.5 | 9.4 | ||
African-American (87) | # | 0 | 0 | 13c | 1 | 0 | 10c | 4 | 15 | |
% | 0 | 0 | 14.9 | 1.2 | 0 | 11.5 | 4.6 | 17.2 | ||
Hispanic (88) | # | 0 | 0 | 2 | 9 | 0 | 0 | 0 | 11 | |
% | 0 | 0 | 2.3 | 10.2 | 0 | 0 | 0 | 12.5 | ||
Asian (25) | # | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 2 | |
% | 0 | 0 | 0 | 4.0 | 0 | 0 | 0 | 8.0 | ||
Control | Caucasian | # | 59/4,2961 | 30/4,2962 | 8/4,2983 | 259/4,2984,10 | 7/4,2975 | 1/3,9536 | 6/3,9807 | 406/4,300 |
% | 1.4 | 0.7 | 0.2 | 6.0 | 0.2 | 0.03 | 0.2 | 9.4 | ||
African-American | # | 7/2,2001 | 3/2,2012 | 274/2,2013,8,9 | 35/2,2034,11 | 0/2,2035 | 169/2,0756,12,13 | 56/2,0867 | 388/2,203 | |
% | 0.3 | 0.1 | 12.4 | 1.6 | 0 | 8.1 | 2.7 | 17.6 | ||
Hispanic | # | - | 1/121 | 1/1218 | 14/12110,11 | - | 0/12112 | 0/121 | 16/121 | |
% | - | 0.8 | 0.8 | 11.6 | - | 0 | 0 | 13.2 | ||
Asian | # | - | 0/286 | 0/2869 | 7/286 | - | 0/28613 | 0/286 | 7/286 | |
% | - | 0 | 0 | 2.4 | - | 0 | 0 | 2.4 |