Epidemiological | number of PM cases per month | |||||||
---|---|---|---|---|---|---|---|---|
Period | PCV7 Serotype | P valueb | Delta6 Serotypec | P value | Non-vaccine Serotype | P value | Total | P value |
Baselined | 15.3 | – | 5.5 | – | 7.5 | – | 28.2 | – |
2003–2004 | –0.1 (–0.66 to 0.78) | 0.87 | +0.2 (–1.22 to 1.65) | 0.77 | –0.9 (–2.64 to 0.90) | 0.33 | –1.3 (–3.87 to 1.22) | 0.30 |
2004–2005 | –2.4 (–3.17 to –1.70) | <0.001 | +0.9 (–0.61 to 2.41) | 0.24 | +3.7 (1.88 to 5.50) | <0.001 | +3.9 (0.69 to 7.15) | 0.017 |
2005–2006 | –4.0 (–4.89 to –3.06) | <0.001 | +1.4 (–0.10 to 2.86) | 0.07 | +1.5 (–0.41 to 3.39) | 0.12 | –1.9 (–5.36 to 1.62) | 0.29 |
2006–2007 | –6.4 (–7.29 to –5.48) | <0.001 | +4.4 (2.86 to 5.89) | <0.001 | +3.4 (1.50 to 5.27) | <0.001 | +2.5 (–1.06 to 5.98) | 0.17 |
2007–2008 | –8.0 (–9.01 to –7.09) | <0.001 | +2.7 (1.19 to 4.28) | <0.001 | +5.0 (3.13 to 6.94) | <0.001 | 0.7 (–2.82 to 4.33) | 0.68 |
2008–2009 | –11.0 (–11.99 to –10.05) | <0.001 | +9.2 (7.76 to 10.79) | <0.001 | +9.0 (7.11 to 11.00) | <0.001 | +6.1 (2.55 to 9.70) | <0.001 |
2009–2010 | –13.1 (–14.11 to –12.09) | <0.001 | +5.4 (3.80 to 6.94) | <0.001 | +9.6 (7.65 to 11.61) | <0.001 | +5.2 (1.47 to 8.79) | 0.006 |
2010–2011 | –12.6 (–13.58 to –11.66) | <0.001 | +3.6 (2.15 to 5.11) | <0.001 | +13.6 (11.74 to 15.56) | <0.001 | +2.9 (–0.66 to 6.44) | 0.11 |
2011–2012 | –12.9 (–13.88 to –11.94) | <0.001 | +1.3 (–0.18 to 2.77) | 0.08 | +11.2 (9.21 to 13.11) | <0.001 | +1.1 (–2.46 to 4.72) | 0.53 |
2012–2013 | –12.8 (–13.87 to –11.79) | <0.001 | –2.4 (–3.91 to –0.81) | 0.003 | +11.3 (9.30 to 13.30) | <0.001 | –3.2 (–6.85 to 0.47) | 0.08 |
2013–2014 | –13.7 (–14.85 to –12.54) | <0.001 | –1.6 (–3.08 to –0.06) | 0.041 | +8.8 (6.68 to 10.88) | <0.001 | –7.1 (–10.85 to –3.35) | <0.001 |