Epidemiological | Number of PM cases per month | |||||||
---|---|---|---|---|---|---|---|---|
Period | PCV7 serotype | P valueb | Delta6 serotypec | P value | Non-vaccine serotype | P value | Total | P value |
Baselined | 5.5 | – | 1.6 | – | 0.8 | – | 8.0 | – |
2003–2004 | +0.2 (–0.26 to 0.67) | 0.39 | –0.1 (–0.76 to 0.56) | 0.76 | –1.2 (–1.74 to –0.65) | <0.001 | +1.3 (–0.02 to 2.70) | 0.05 |
2004–2005 | –1.2 (–1.69 to –0.75) | <0.001 | +0.3 (–0.36 to 0.97) | 0.37 | +0.8 (0.23 to 1.42) | 0.007 | +1.0 (–0.39 to 2.36) | 0.16 |
2005–2006 | –3.0 (–3.51 to –2.59) | <0.001 | +0.1 (–0.54 to 0.78) | 0.72 | +0.3 (–0.26 to 0.91) | 0.28 | –1.1 (–2.47 to 0.20) | 0.09 |
2006–2007 | –3.2 (–3.64 to 2.70) | <0.001 | +1.5 (0.84 to 2.16) | <0.001 | +0.3 (–0.22 to 0.93) | 0.23 | +0.2 (1.11 to 1.58) | 0.73 |
2007–2008 | –4.2 (–4.64 to –3.71) | <0.001 | +0.4 (–0.26 to 1.07) | 0.23 | +1.2 (0.61 to 1.77) | <0.001 | –1.0 (–2.38 to 0.32) | 0.14 |
2008–2009 | –5.1 (–5.56 to –4.56) | <0.001 | +1.8 (1.14 to 2.49) | <0.001 | +1.0 (0.42 to 1.65) | <0.001 | +1.7 (0.31 to 3.05) | 0.016 |
2009–2010 | –4.6 (–5.14 to –4.15) | <0.001 | +1.5 (0.82 to 2.19) | <0.001 | +2.0 (1.44 to 2.65) | <0.001 | +1.0 (–0.34 to 2.45) | 0.13 |
2010–2011 | –4.8 (–5.27 to –4.35) | <0.001 | +0.7 (0.01 to 1.34) | 0.045 | +3.3 (2.74 to 3.92) | <0.001 | –0.6 (–1.93 to 0.75) | 0.38 |
2011–2012 | –5.4 (–5.82 to –4.90) | <0.001 | +0.5 (–0.15 to 1.16) | 0.13 | +2.1 (1.56 to 2.71) | <0.001 | –1.6 (–2.92 to –0.26) | 0.019 |
2012–2013 | –4.7 (–5.24 to –4.21) | <0.001 | –0.3 (–1.04 to 0.33) | 0.31 | +3.9 (3.31 to 4.54) | <0.001 | –2.7 (–4.14 to –1.36) | <0.001 |
2013–2014 | –5.2 (–5.71 to –4.62) | <0.001 | –0.3 (–0.93 to 0.39) | 0.42 | +1.7 (1.09 to 2.37) | <0.001 | –3.5 (–4.81 to –2.13) | <0.001 |