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Table 5 Association between hospital exposures and mobility outcomes according to study group

From: The effect of intervening hospitalizations on the benefit of structured physical activity in promoting independent mobility among community-living older persons: secondary analysis of a randomized controlled trial

 

Physical activity (N = 818)

Health education (N = 817)

 
 

Outcome rate per 100 person-year

 

Outcome rate per 100 person-year

 

Exposurea

Hospitalized

Not hospitalized

HR (95% CI)

Hospitalized

Not hospitalized

HR (95% CI)

P value*

 

Onset of MMD

Any hospitalization

39 (31–48)

10 (8–13)

3.3 (2.5–4.3)

46 (37–59)

14 (11–16)

3.2 (2.5–4.1)

0.903

Number of hospitalizations

 0 (ref)

 

10 (8–13)

1.0

 

14 (11–16)

1.0

0.742

 1

36 (28–46)

 

3.0 (2.2–4.0)

39 (30–51)

 

2.7 (2.0–3.6)

 

 2 or more

50 (34–73)

 

4.3 (2.8–6.8)

79 (57–109)

 

5.1 (3.4–7.6)

 

Number of days hospitalizedb

 0 (ref)

 

13 (11–15)

1.0

 

16 (13–19)

1.0

0.804

 3

15 (13–18)

 

1.2 (1.2–1.3)

19 (16–23)

 

1.2 (1.2–1.3)

 

 10

23 (19–28)

 

1.9 (1.6–2.1)

29 (24–36)

 

1.9 (1.6–2.2)

 

Any hospitalizationc

Recovery from MMD d

 Model 1

43 (27–69)

64 (46–89)

0.60 (0.35–1.04)

33 (21–53)

51 (37–70)

0.51 (0.28–0.90)

0.670

 Model 2

52 (33–80)

71 (50–99)

0.59 (0.39–0.88)

34 (21–54)

56 (40–77)

0.45 (0.27–0.74)

0.392

 Model 3

43 (27–68)

64 (46–89)

0.60 (0.35–1.03)

33 (21–53)

51 (37–69)

0.51 (0.29–0.92)

0.688

  1. Abbreviations: CI confidence interval, HR hazard ratio, MMD major mobility disability, ref reference group
  2. * Values represent statistical interaction between exposure and study group on mobility outcome
  3. aAssessed during the interval preceding the outcome
  4. b Values for outcome rates are provided for a range of fixed values assuming a log-linear relationship. Three days was the median length of hospital stay, and 10 days allowed for long lengths of stay and more than one hospital admission
  5. c Results are not available for the number of hospitalizations or number of days hospitalized because the number of participants with more than one hospitalization during the at-risk period was small
  6. d All models include clinical site, age, and gender as covariates; Model 2 uses inverse probability weighting based on MMD, whereas Model 3 uses inverse probability weighting based on withdrawal/missed follow-up, as described in the Methods