Table 3 Reported culprits of drug-induced anaphylaxis according to drug category

Total number of patients with reported drug-induced anaphylaxis

1325

Drug class/name

 Anti-infectives, n (%)

544 (41.1)

 Beta-lactams, n (%)

402 (30.3)

 Quinolones, n (%)

30 (2.3)

 Macrolides, n (%)

25 (1.9)

 Aminoglycosides, n (%)

24 (1.8)

 Glycopeptides, n (%)

19 (1.4)

 Anti-protozoals, n (%)

13 (1.0)

 Sulphonamides, n (%)

9 (0.7)

 Tetracyclines, n (%)

9 (0.7)

 Anti-fungals, n (%)

4 (0.3)

 Lincosamides, n (%)

3 (0.2)

 Anti-virals, n (%)

2 (0.2)

 Anti-mycobacterials, n (%)

1 (0.1)

 Other anti-infectives, n (%)

3 (0.2)

 Musculoskeletal system, n (%)

158 (11.9)

 Nervous system, n (%)

157 (11.8)

 Anaesthesia, n (%)

155 (11.7)

 Immune system and malignant diseases, n (%)

99 (7.5)

 Gastrointestinal system, n (%)

46 (3.5)

 Respiratory system, n (%)

28 (2.1)

 Blood and nutrition, n (%)

25 (1.9)

 Skin, n (%)

19 (1.4)

 Cardiovascular system, n (%)

19 (1.4)

 Eye, n (%)

12 (0.9)

 Endocrine system, n (%)

10 (0.8)

 Ear, nose and throat, n (%)

6 (0.5)

 Vaccines, n (%)

4 (0.3)

 Genito-urinary system, n (%)

1 (0.1)

 Emergency treatment of poisoning, n (%)

1 (0.1)

 Unknown drug culprit, n (%)

40 (3.0)