Fig. 2

Drakenstein Child Health Study cohort flow chart of children with neuroimaging by HIV exposure. *Selection criteria for neuroimaging are fully described in methods. Inclusion criteria are as follows: (i) currently active in the cohort; (ii) residing in the study area; (iii) child aged 2–3 years. Exclusion criteria are as follows: (i) medical comorbidity (genetic syndrome, neurological disorder, or congenital abnormality); (ii) gestation < 36 weeks; (iii) low Apgar score (< 7 at 5 min); (iv) neonatal intensive care admission; (v) maternal use of illicit drugs during pregnancy; (vi) MRI contraindications; (vii) child HIV infection