Basic characteristics | Summary |
---|---|
Region of corresponding author (review level) | N = 151 |
 Africa | 9 (5.96%) |
 Americas (North and South) | 32 (21.19%) |
 Asia | 68 (45.03%) |
 Europe | 40 (26.49%) |
 Oceania | 2 (1.32%) |
Number of trials included (review level) | 16 (IQR: 10 to 26) |
 1 to 9 (minimum was 5) | 36 (23.84%) |
 10 to 29 | 83 (54.30%) |
 30 or more (maximum was 195) | 33 (21.85%) |
Effect estimates (review level) | |
 Odds ratio (including Peto odds ratio) | 47 (31.13%) |
 Risk ratio | 96 (63.58%) |
 Risk difference | 3 (1.99%) |
 Others (e.g., HR, IRR, or above combinations) | 5 (3.31%) |
Protocol (review level) | |
 Yes | 43 (28.48%) |
 No | 108 (71.52%) |
Registration (study level) | N = 10,069 |
 Yes | 7483 (74.32%) |
 No | 2408 (23.91%) |
 Missing | 178 (1.77%) |
Center (study level) | |
 Multiple centers | 7891 (78.37%) |
 Single center | 350 (3.48%) |
 Missing | 1828 (18.15%) |
Funding (study level) | |
 Industry | 8440 (83.82%) |
 Industry and academic | 108 (1.07%) |
 Academic | 737 (7.32%) |
 No funding | 3 (0.03%) |
 Missing | 781 (7.76) |
Publication type of study (study level) | |
 Article | 9848 (97.81%) |
 Abstract | 18 (0.18%) |
 Registration only (unpublished) | 198 (1.97%) |
 Non-RCT (further removed) | 5 (0.05%) |
Accessible of full-text (study level) | N = 9,848 |
 Yes | 9598 (97.46%) |
 No | 250 (2.54%) |