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Table 4 Summary of multivariable Cox Regression model to assess the independent association of IgG and IgA against S and N antigens with breakthrough infection

From: Correlates of protection and determinants of SARS-CoV-2 breakthrough infections 1 year after third dose vaccination

Antibody

HR

Upper CI

Lower CI

p-value

IgG S Omicron

0.12

0.50

0.027

0.004

IgA S Omicron

0.48

1.23

0.19

0.13

IgG N Wuhan

0.59

0.93

0.37

0.025

IgA N Wuhan

1.25

2.16

0.72

0.417

  1. Covariates for adjustment included age, comorbidities, chronic medication, sex, smoking, and vaccination with 3 doses (ref: 2 doses), and type of primary vaccination. N = 359
  2. HR hazard ratio