Table 5 Smoking-related characteristics according to the genetic risk group of HNSCC

Status

 Smoking status (UKBB field: 20116), No. (%)

 < .001

  Never

41,282 (54.2%)

40,837 (53.1%)

40,711 (53.0%)

39,893 (51.6%)

  Previous

27,655 (36.3%)

28,229 (36.7%)

28,071 (36.5%)

28,367 (36.7%)

  Current

7270 (9.5%)

7834 (10.2%)

8099 (10.5%)

9101 (11.8%)

 Current tobacco smoking  (UKBB field: 1239), No. (%)

 < .001

  No

69,176 (90.5%)

69,291 (89.8%)

68,988 (89.5%)

68,527 (88.3%)

  Only occasionally

2001 (2.6%)

1997 (2.6%)

2012 (2.6%)

2096 (2.7%)

  Yes

5269 (6.9%)

5837 (7.6%)

6087 (7.9%)

7005 (9.0%)

Amount

 Number of cigarettes previously smoked daily (UKBB field: 2887), mean ± SD

19.0 ± 10.5

19.5 ± 10.7

19.4 ± 10.6

19.7 ± 10.8

 < .001

 Pack years of smoking (UKBB field: 20161), mean ± SD

23.6 ± 18.9

24.1 ± 19.2

24.5 ± 19.5

25.3 ± 19.7

 < .001

History

 Past tobacco smoking  (UKBB field: 1249), No. (%)

 < .001

  Smoked on most or all days

18,951 (26.6%)

19,780 (27.7%)

19,716 (27.8%)

20,420 (28.9%)

  Smoked occasionally

10,381 (14.6%)

10,178 (14.3%)

10,112 (14.2%)

9833 (13.9%)

  Just tried once or twice

11,203 (15.7%)

10,801 (15.1%)

10,621 (15.0%)

10,066 (14.3%)

  I have never smoked

30,603 (43.0%)

30,542 (42.8%)

30,584 (43.1%)

30,284 (42.9%)

 Maternal smoking around birth (UKBB field: 1787), No. (%)

 < .001

  No

46,341 (70.3%)

45,699 (68.8%)

44,992 (67.9%)

43,882 (66.0%)

  Yes

19,532 (29.7%)

20,716 (31.2%)

21,318 (32.1%)

22,587 (34.0%)

 Age stopped smoking  (UKBB field: 2897), mean ± SD

40.3 ± 11.9

40.3 ± 11.9

40.5 ± 11.8

40.7 ± 11.9

 < .001

 Number of unsuccessful stop-smoking attempts  (UKBB field: 2926), mean ± SD

2.9 ± 7.0

3.0 ± 6.8

3.0 ± 7.9

3.1 ± 7.5

.006