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Table 3 The association between air pollutants exposure (per 10 μg/m3) and incident CVD in different lifestyle categories, and the mediation effect of lifestyle categories to air pollution in CVD

From: The role of lifestyle in the association between long-term ambient air pollution exposure and cardiovascular disease: a national cohort study in China

 

Unfavorable

HR (95% CI)

Intermediate

HR (95% CI)

Favorable

HR (95% CI)

Mediation proportion (%) (95% CI)

PM1

   

8.0 (3.6–17.8)

 Model 1

1.15 (1.04–1.28)

1.09 (1.04–1.14)

0.97 (0.84–1.13)

 

 P value

0.008

0.001

0.697

 

 Model 2

1.17 (1.05–1.31)

1.08 (1.03–1.13)

0.97 (0.83–1.14)

 

 P value

0.005

0.003

0.762

 

PM2.5

   

14.3 (5.6–54.1)

 Model 1

1.12 (1.02–1.23)

1.04 (1.00–1.09)

0.97 (0.85–1.10)

 

 P value

0.020

0.058

0.591

 

 Model 2

1.13 (1.02–1.24)

1.03 (0.98–1.07)

0.96 (0.84–1.10)

 

 P value

0.016

0.238

0.552

 

PM10

   

7.4 (3.8–13.3)

 Model 1

1.09 (1.03–1.14)

1.05 (1.02–1.07)

1.01 (0.94–1.08)

 

 P value

0.001

< 0.001

0.798

 

 Model 2

1.09 (1.04–1.15)

1.04 (1.02–1.07)

1.01 (0.94–1.09)

 

 P value

0.001

< 0.001

0.751

 

NO2

   

12.0 (6.3–24.6)

 Model 1

1.21 (1.06–1.38)

1.09 (1.03–1.16)

0.97 (0.80–1.17)

 

 P value

0.004

0.005

0.751

 

 Model 2

1.25 (1.09–1.44)

1.08 (1.01–1.15)

0.98 (0.80–1.20)

 

 P value

0.001

0.017

0.819

 

O3

   

-

 Model 1

1.21 (0.98–1.50)

1.03 (0.93–1.14)

0.83 (0.59–1.16)

 

 P value

0.056

0.920

0.419

 

 Model 2

1.24 (0.99–1.54)

1.00 (0.90–1.11)

0.87 (0.62–1.22)

 

 P value

0.071

0.556

0.279

 
  1. Model 1: crude model
  2. Model 2: adjusted for age, sex, education level, residence, alcohol consumption, and income
  3. Abbreviations: CI Confidence interval, CVD Cardiovascular disease, HR Hazard ratio, NO2 Nitrogen dioxide, O3 Ozone, PM1 Particulate matter with an aerodynamic diameter less than 1 μm, PM2.5 Particulate matter with an aerodynamic diameter less than 2.5 μm, PM10 Particulate matter with an aerodynamic diameter < 10 μm