Table 3 Treatment emergent adverse events (TEAEs) occurring at least 5% of patients
Events, n (%) | All | Grade 1 | Grade 2 | Grade 3 | Grade 4 |
|---|---|---|---|---|---|
At least one TEAE | 41 (97.6) | 7 (16.7) | 21 (50.0) | 12 (28.6) | 1 (2.4) |
ALT increased | 24 (57.1) | 22 (52.4) | 1 (2.4) | 1 (2.4) | 0 |
Neutrophil count decreased | 20 (47.6) | 6 (14.3) | 8 (19.0) | 6 (14.3) | 0 |
Vomiting | 19 (45.2) | 10 (23.8) | 8 (19.0) | 1 (2.4) | 0 |
Nausea | 18 (42.9) | 17 (40.5) | 1 (2.4) | 0 | 0 |
White blood cell decreased | 16 (38.1) | 4 (9.5) | 9 (21.4) | 2 (4.8) | 1 (2.4) |
AST increased | 15 (35.7) | 13 (31.0) | 2 (4.8) | 0 | 0 |
RCCEP | 15 (35.7) | 15 (35.7) | 0 | 0 | 0 |
Hypertriglyceridemia | 15 (35.7) | 13 (31.0) | 1 (2.4) | 1 (2.4) | 0 |
Platelet count decreased | 15 (35.7) | 11 (26.2) | 2 (4.8) | 2 (4.8) | 0 |
Hyperuricemia | 6 (14.3) | 6 (14.3) | 0 | 0 | 0 |
LDH increased | 5 (11.9) | 5 (11.9) | 0 | 0 | 0 |
Anemia | 5 (11.9) | 5 (11.9) | 0 | 0 | 0 |
Fever | 4 (9.5) | 4 (9.5) | 0 | 0 | 0 |
Infectious pneumonia | 4 (9.5) | 0 | 4 (9.5) | 0 | 0 |
Interstitial pneumonia | 4 (9.5) | 0 | 2 (4.8) | 2 (4.8) | 0 |
Pruritus | 4 (9.5) | 3 (7.1) | 1 (2.4) | 0 | 0 |
Anorexia | 4 (9.5) | 4 (9.5) | 0 | 0 | 0 |
Hypokalemia | 3 (7.1) | 3 (7.1) | 0 | 0 | 0 |