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Table 2 Risk of hip fracture by Rx-Risk category in women and men ≥ 51 years

From: The medication-based Rx-Risk Comorbidity Index and risk of hip fracture - a nationwide NOREPOS cohort study

 

Total no. of hip fractures

Total no. of person years

Incidence rate ratioa

95% CI

Women

 Rx-Risk ≤ 0

10,889

3,372,375

1.0

(ref)

 Rx-Risk 1–5

19,141

3,130,998

1.4

(1.3, 1.4)

 Rx-Risk 6–10

15,486

1,509,573

1.8

(1.8, 1.9)

 Rx-Risk 11–15

7,810

527,277

2.4

(2.3, 2.4)

 Rx-Risk 16–20

3,140

158,307

3.1

(3.0, 3.3)

 Rx-Risk 21–25

940

38,786

4.1

(3.8, 4.4)

 Rx-Risk > 25

289

9,686

6.1

(5.4, 6.8)

 Rx-Risk missingb

6409

1,050,396

1.6

(1.6, 1.7)

Men

 Rx-Risk ≤ 0

5,528

3,024,640

1.0

(ref)

 Rx-Risk 1–5

9,515

2,914,461

1.5

(1.4, 1.5)

 Rx-Risk 6–10

6,622

1,122,501

2.2

(2.1, 2.3)

 Rx-Risk 11–15

3,280

341,269

3.1

(3.0, 3.3)

 Rx-Risk 16–20

1,349

96,685

4.3

(4.0, 4.6)

 Rx-Risk 21–25

443

25,568

5.4

(4.9, 6.0)

 Rx-Risk > 25

142

7,179

7.1

(6.0, 8.3)

 Rx-Risk missingb

3121

1,514,911

1.7

(1.6, 1.8)

  1. The Norwegian Prescription Database (2005-2016) and the NOREPOS Hip Fracture Database (2006–2017)
  2. aAdjusted for birth year and calendar year
  3. bIncludes individuals who had not filled a prescription for any of the medications included in the Rx-Risk Comorbidity Index in a calendar year