Table 3 Net clinical benefits for each treatment according to different weight models
Stroke prevention strategy | NCB based on different weight models, % per year (95% CI) | ||
|---|---|---|---|
Relative weight of ICH compared to ischemic stroke according to Singer et al.[20] Weight = 1.5 | Relative weight of ICH compared to ischemic stroke according to Connolly et al.[21] Weight = 3.08 | Relative weight of ICH compared to ischemic stroke according to Lip et al.[22] Weight = 2.44 | |
Compared to AP (Reference group) | – | – | – |
NOACs | 3.65 (3.32 to 3.98) | 3.84 (3.63 to 4.05) | 3.76 (3.45 to 4.07) |
Warfarin | -2.13 (-2.28 to -1.98) | -2.46 (-2.56 to -2.36) | -2.32 (-2.45 to -2.19) |
AP + NOACs | -2.87 (-3.00 to -2.74) | -2.81 (-2.90 to -2.72) | -2.83 (-2.94 to -2.72) |
AP + Warfarin | -1.80 (-1.95 to -1.64) | -2.28 (-2.39 to -2.18) | -2.09 (-2.22 to -1.95) |