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Table 3 Risk of meningitis after COVID-19 vaccination, overall and stratified by scheduled dose and vaccine type

From: Risk of encephalitis and meningitis after COVID-19 vaccination in South Korea: a self-controlled case series analysis

 

No. event

Person-years

Incidence ratea

IRR (95% CI)

Risk

Control

Risk

Control

Risk

Control

Meningitis

 Overall

398

964

252.8

628.9

1.57

1.53

1.03 (0.91–1.16)

 Scheduled dose

  1st dose

178

964

105.4

628.9

1.69

1.53

1.10 (0.94–1.29)

  2nd dose

147

784

98.3

478.1

1.50

1.64

0.91 (0.76–1.09)

  3rd dose

73

134

49.2

68.6

1.49

1.95

0.76 (0.57–1.00)

 Vaccine type

  BNT162b2

213

509

137.1

326.9

1.55

1.56

1.00 (0.85–1.17)

  mRNA-1273

59

156

41.9

104.4

1.41

1.49

0.94 (0.69–1.29)

  ChAdOx1-S

41

106

19.3

72.3

2.12

1.47

1.45 (0.99–2.11)

  Ad26.COV2.S

4

7

0.8

6.2

4.74

1.12

4.22 (1.22–14.59)

  1. Abbreviations: COVID-19 Coronavirus infectious disease 2019, IRR Incidence rate ratio, CI Confidence interval
  2. aPer person-year