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Fig. 6 | BMC Medicine

Fig. 6

From: Delivering synaptic protein mRNAs via extracellular vesicles ameliorates cognitive impairment in a mouse model of Alzheimer’s disease

Fig. 6

Characterization of EVs. A, B Size distribution of wild-type (A, 97.3 ± 42.8 nm) and transfected EVs (B, 99.5 ± 41.0 nm) measured using nanoparticle tracking analysis. C Protein levels of the EV markers Alix, TSG101, CD63, and APOB measured using Western blot analysis. D Transmission electron microscope image showing the distinctive spherical-shaped morphology of EVs. Scale bar = 100 nm. APOB, apolipoprotein B; EVs, extracellular vesicles; EVs-TNGS, extracellular vesicles targeting neural cells overexpressing Gap43 and Snap25; TSG101, tumor susceptibility gene 101

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BMC Medicine

ISSN: 1741-7015

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