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Fig. 3 | BMC Medicine

Fig. 3

From: Lipid metabolic reprogramming mediated by circulating Nrg4 alleviates metabolic dysfunction-associated steatotic liver disease during the early recovery phase after sleeve gastrectomy

Fig. 3

Gene deletion of Nrg4 increased susceptibility to MASLD and decreased the therapeutic effect of SG. A Schematic diagram of the rodent model construction. B Representative images of mouse liver tissue section morphology and H&E and Oil Red O staining. C Comparisons of the relative area of lipid droplets among the different groups of mice. D Comparisons of the serum Nrg4 concentration among different mouse models. * indicates p < 0.05, 2* indicates p < 0.01, 3* indicates p < 0.001, 4* indicates p < 0.0001. The color indicates the compared group. E Correlation analysis between Nrg4 and the relative area of lipid droplets in different mouse models

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