Fig. 4
Catalonia DDI network. Nodes denote drugs involved in at least one co-administration known to be a DDI. Only nodes connected via edges with a strength of interaction larger than 0.18 are shown for clarity. Node color represents the highest level of primary action class, as retrieved from drugs.com. Node sizes are proportional to the probability of patients being affected by a DDI involving the drug (P(UiΦ)). Edge weights denote the strength of interaction (co-administration length). Edge colors denote relative risk (RR) for women (red) or men (blue). Color intensity for relative risks varies in [1, 5]; that is, values are clipped at 5 for clarity