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Table 1 Relative risk for women (RRW) of drug co-administration (RRC) and interactions (RRI); the latter is also computed for types of interactions as per drugs.com (minor, moderate, and major). The percentage of patients of each gender (M, man; W, woman) for each case is also shown. Values shown for all three populations during the first 18 months of the study. Asterisks denote statistically significant differences based on Fisher’s exact test results

From: Prevalence and differences in the co-administration of drugs known to interact: an analysis of three distinct and large populations

 

Blumenau

Catalonia

Indianapolis

RRW

% W, M

RRW

% W, M

RRW

% W, M

Co-administration (RRCW)

1.07*

(79.08%, 74.06%)

1.05*

(77.39%, 73.88%)

1.06*

(77.88%, 71.82%)

Interaction (RRIW)

1.54*

(14.64%, 9.49%)

1.25*

(11.08%, 8.84%)

1.12*

(12.69%, 11.36%)

Minor interaction

0.81*

(0.36%, 0.44%)

1.27*

(0.26%, 0.2%)

1.02

(1.13%, 1.1%)

Moderate interaction

1.59*

(11.3%, 7.1%)

1.4*

(8.31%, 5.93%)

1.12*

(10.67%, 9.49%)

Major interaction

1.53*

(6.25%, 4.07%)

1.08*

(3.17%, 2.95%)

1.02

(4.87%, 4.76%)