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Table 1 Baseline characteristics of the risk factors used in the Rotterdam Ischemic Heart Disease and Stroke Computer Simulation (RISC) model for the 3,478 Rotterdam study participants and 25,492 European Prospective Investigation of Cancer (EPIC)-Norfolk study participants

From: Validation of a model to investigate the effects of modifying cardiovascular disease (CVD) risk factors on the burden of CVD: the rotterdam ischemic heart disease and stroke computer simulation (RISC) model

Variable RISC (n = 3,478) EPIC (n = 25,492)
Age 69.0 (62 to 75) 59.2 (51 to 67)
Male subjects, % 39% 45%
Smoker   
   Never 34.5% 46.0%
   Former 41.9% 42.3%
   Current 23.6% 11.7%
BMI 26.3 (23.8 to 28.5) 26.3 (23.7 to 28.4)
WHR 0.91 (0.84 to 0.97) 0.86 (0.78 to 0.93)
Systolic BP 140.0 (124 to 155) 135.5 (122.5 to 146.5)
Diastolic BP 74.1 (66 to 82) 82.5 (74.5 to 89.5)
Hypertension 36.4% 29.9%
Total cholesterol 6.67 (5.8 to 7.4) 6.19 (5.4 to 6.9)
HDL cholesterol 1.34 (1.1 to 1.5) 1.41 (1.1 to 1.6)
Glucoseb 6.93 (5.5 to 7.5) 6.67 (5.5 to 7.3)
Creatinine 82.5 (72 to 91) 86.7 (76 to 97)
Diabetes mellitus 10.7% 12.2%
Angina pectorisb 10.4% 9.2%
Atrial fibrillationb 2.5% 2.9%
Intermittent claudicationb 2.1% 1.5%
TIAb 5.1% 4.8%
CVD 17.8% 4.3%
Family history of MI 16.3% 18.4%
Family history of CVD 23.0% 23.3%
  1. Abbreviations: BMI, body mass index; BP, blood pressure; CVD, cardiovascular disease; MI, myocardial infarction; TIA, transient ischemic attack; WHR, waist-to-hip ratio.
  2. aAverage values and inter-quartile ranges (brackets) are given for continuous variables, while categorical variables are given as percentages.
  3. bIndicates imputed risk factors for the EPIC-Norfolk dataset.