Table 1 Baseline characteristics of the risk factors used in the Rotterdam Ischemic Heart Disease and Stroke Computer Simulation (RISC) model for the 3,478 Rotterdam study participants and 25,492 European Prospective Investigation of Cancer (EPIC)-Norfolk study participants

Age

69.0 (62 to 75)

59.2 (51 to 67)

Male subjects, %

39%

45%

Smoker

   Never

34.5%

46.0%

   Former

41.9%

42.3%

   Current

23.6%

11.7%

BMI

26.3 (23.8 to 28.5)

26.3 (23.7 to 28.4)

WHR

0.91 (0.84 to 0.97)

0.86 (0.78 to 0.93)

Systolic BP

140.0 (124 to 155)

135.5 (122.5 to 146.5)

Diastolic BP

74.1 (66 to 82)

82.5 (74.5 to 89.5)

Hypertension

36.4%

29.9%

Total cholesterol

6.67 (5.8 to 7.4)

6.19 (5.4 to 6.9)

HDL cholesterol

1.34 (1.1 to 1.5)

1.41 (1.1 to 1.6)

Glucose^b

6.93 (5.5 to 7.5)

6.67 (5.5 to 7.3)

Creatinine

82.5 (72 to 91)

86.7 (76 to 97)

Diabetes mellitus

10.7%

12.2%

Angina pectoris^b

10.4%

9.2%

Atrial fibrillation^b

2.5%

2.9%

Intermittent claudication^b

2.1%

1.5%

TIA^b

5.1%

4.8%

CVD

17.8%

4.3%

Family history of MI

16.3%

18.4%

Family history of CVD

23.0%

23.3%