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Research: Liver toxicity and tuberculosis chemotherapy

Drug-induced liver injury (DILI) commonly occurs during tuberculosis treatment, data from the REMoxTB trial provide evidence of the risk of DILI in patients on standard treatment, suggesting that monitoring of hepatic enzymes in the first two months should be standard of care.

Research: Consumption of different protein sources and physical functioning

A longitudinal study reveals higher processed meat intake can lead to impaired agility and poor lower-extremity function, which can be reduced by substituting this meat with other protein sources.

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Debate: Are “pragmatic” trials of medicines actually pragmatic?

In a new Debate article, John Ioannidis and colleagues question how researchers label their medicine RCTs as “pragmatic”, and discuss recommendations for improvements.

Correspondence: Impact of gender gap in a deparment of medicine

Women remain underrepresented in academic medical centers, qualitative data from a Canadian department of medicine indicates the existing gender hap in academic medicine may have negative consequences for organizational effectiveness and workplace culture.

Aims and scope

BMC Medicine is the flagship medical journal of the BMC series. An open access, open peer-reviewed general medical journal, BMC Medicine publishes outstanding and influential research in all areas of clinical practice, translational medicine, medical and health advances, public health, global health, policy, and general topics of interest to the biomedical and sociomedical professional communities. We also publish stimulating debates and reviews as well as unique forum articles and concise tutorials.  

Articles

Most accessed (recent)

Research
Potential predatory and legitimate biomedical journals: can you tell the difference? A cross-sectional comparison
Larissa Shamseer, David Moher, Onyi Maduekwe, Lucy Turner, Virginia Barbour, Rebecca Burch, Jocalyn Clark, James Galipeau, Jason Roberts and Beverley J. Shea  
Published: 16th March 2017

Minireview
Procalcitonin-guided diagnosis and antibiotic stewardship revisited
Ramon Sager, Alexander Kutz, Beat Mueller and Philipp Schuetz
Published: 24th January 2017

Research
The potential impact of Brexit and immigration policies on the GP workforce in England: a cross-sectional observational study of GP qualification region and the characteristics of the areas and population they served in September 2016
Aneez Esmail, Maria Panagioti and Evangelos Kontopantelis
Published: 16th November 2017

Research
The potential impact of food taxes and subsidies on cardiovascular disease and diabetes burden and disparities in the United States
José L. Peñalvo, Frederick Cudhea, Renata Micha, Colin D. Rehm, Ashkan Afshin, Laurie Whitsel, Parke Wilde, Tom Gaziano, Jonathan Pearson-Stuttard, Martin O’Flaherty, Simon Capewell and Dariush Mozaffarian
Published: 27th November 2017

Review
Emerging concepts in liquid biopsies
Samantha Perakis and Michael R. Speicher
Published: 6th April 2017

Source: Google analytics

Review
Cancer immunotherapy: the beginning of the end of cancer?
Sofia Farkona, Eleftherios P. Diamandis and Ivan M. Blasutig
Published: 5th May 2016

Correspondence
Cancer and fertility preservation: international recommendations from an expert meeting
Matteo Lambertini, Lucia Del Mastro, Maria C. Pescio, Claus Y. Andersen, Hatem A. Azim Jr., Fedro A. Peccatori, Mauro Costa, Alberto Revelli, Francesca Salvagno, Alessandra Gennari, Filippo M. Ubaldi, Giovanni B. La Sala, Cristofaro De Stefano, W. Hamish Wallace, Ann H. Partridge and Paola Anserini
Published: 4th January 2016

Review
The impact of migration on tuberculosis epidemiology and control in high-income countries: a review
Manish Pareek, Christina Greenaway, Teymur Noori, Jose Munoz and Dominik Zenner
Published: 23rd March 2016

Minireview
Advances in immunotherapy for melanoma
Jason M. Redman, Geoffrey T. Gibney and Michael B. Atkins
Published: 6th February 2016

Review
The global threat of Zika virus to pregnancy: epidemiology, clinical perspectives, mechanisms, and impact
Phillipe Boeuf, Heidi E. Drummer, Jack S. Richards, Michelle J. L. Scoullar and James G. Beeson
Published: 3rd August 2016

Source: Web of Science

Correspondence
CONSORT 2010 Statement: updated guidelines for reporting parallel group randomised trials
Kenneth F Schulz, Douglas G Altman and David Moher
Published: 24 March 2010

Debate
Toward the future of psychiatric diagnosis: the seven pillars of RDoC
Bruce N Cuthbert and Thomas R Insel
Published: 14 May 2013

Research
Collagen reorganization at the tumor-stromal interface facilitates local invasion
Paolo P Provenzano, Kevin W Eliceiri, Jay M Campbell, David R Inman, John G White and Patricia J Keely
Published: 26 December 2006

Research
miR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cells
Joachim Silber, Daniel A Lim, Claudia Petritsch, Anders I Persson, Alika K Maunakea, Mamie Yu, Scott R Vandenberg, David G Ginzinger, C David James, Joseph F Costello, Gabriele Bergers, William A Weiss, Arturo Alvarez-Buylla and J Graeme Hodgson
Published: 24 June 2008

Research
Cross-national epidemiology of DSM-IV major depressive episode
Evelyn Bromet, Laura Helena Andrade, Irving Hwang, Nancy A Sampson, Jordi Alonso, Giovanni de Girolamo, Ron de Graaf, Koen Demyttenaere, Chiyi Hu, Noboru Iwata, Aimee N Karam, Jagdish Kaur, Stanislav Kostyuchenko, Jean-Pierre Lépine, Daphna Levinson, Herbert Matschinger, Maria Elena Medina Mora, Mark Oakley Browne, Jose Posada-Villa, Maria Carmen Viana, David R Williams and Ronald C Kessler
Published: 26 July 2011

Source Web of Science

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Call for papers

Spatial epidemiology and infectious diseases
Guest Editors: Prof Sally Blower and Prof Gerardo Chowell  
Submission deadline: 15th March 2018

World TB Day
Guest editors: Prof Ibrahim Abubakar, Dr Helen Fletcher, Dr Marc Lipman and Prof Tim McHugh
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Article collections

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Migrant and refugee health
Guest editors: Prof Alimuddin Zumla and Prof Ibrahim Abubakar

Article collection
Managing liver disease

Article collection
Gout diagnosis, management and therapy
Guest editor: Prof Jasvinder Singh

See all article collections here.

Systematic reviews

Every year, BMC Medicine publishes several systematic reviews that can inform evidence-based interventions, treatment approaches, and policies within clinical and/or population health settings, and across a variety of countries and global issues. Click here for a list of recent systematic reviews that may be of interest to our readership and other key stakeholders in designing clinical or global health interventions.  

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Read our new content commissioned by BMC Medicine editors from leading researchers:

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