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Article collection: Beyond Big Data to new Biomedical and Health Data Science: moving to next century precision health

We are pleased to launch our new collection which provides examples on how big-data driven approaches might ultimately improve health outcomes and addresses data complexity, challenges facing this type of research, and other enablers and barriers. 

Research: Modelling the impact of Wolbachia on dengue

Using a combination of multiple modelling methods, it is estimated that a nationwide introduction of Wolbachia-infected mosquitoes in Indonesia could significantly reduce the transmission of dengue, findings which have implications for future strategies to alleviate dengue burden.

Research: Blood pressure trends in normal pregnancies

Findings from a systematic review indicate heart rate increases during pregnancies are lower than previously thought, highlighting manual and automated blood pressure measurements cannot be used interchangeably, and consistent methods should be used throughout gestation.

Research: A dynamic neural network model for predicting risk of Zika in real time

A neural network model – incorporating environmental, epidemiological, socioeconomic, population and travel data – was applied to the 2015–2016 Zika outbreak in the Americas. The model accurately predicted the geographic spread of the outbreak, particularly during shorter time windows.

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Aims and scope

BMC Medicine is the flagship medical journal of the BMC series. An open access, open peer-reviewed general medical journal, BMC Medicine publishes outstanding and influential research in all areas of clinical practice, translational medicine, medical and health advances, public health, global health, policy, and general topics of interest to the biomedical and sociomedical professional communities. We also publish stimulating debates and reviews as well as unique forum articles and concise tutorials.  

Articles

Most accessed (recent)

Research article | 29th November 2018
Sauna bathing is associated with reduced cardiovascular mortality and improves risk prediction in men and women: a prospective cohort study
Tanjaniina Laukkanen, Setor K. Kunutsor, Hassan Khan, Peter Willeit, Francesco Zaccardi and Jari A. Laukkanen
 

Research article | 11th January 2019
Morbidity, mortality and missed appointments in healthcare: a national retrospective data linkage study
Ross McQueenie, David A. Ellis, Alex McConnachie, Philip Wilson and Andrea E. Williamson

Research article | 10th January 2019
The impact of repeated vaccination on influenza vaccine effectiveness: a systematic review and meta-analysis
Lauren C. Ramsay, Sarah A. Buchan, Robert G. Stirling, Benjamin J. Cowling, Shuo Feng, Jeffrey C. Kwong and Bryna F. Warshawsky

Research article | 15th January 2019
Serious adverse events reported in placebo randomised controlled trials of oral naltrexone: a systematic review and meta-analysis
Monica Bolton, Alex Hodkinson, Shivani Boda, Alan Mould, Maria Panagioti, Sarah Rhodes, Lisa Riste and Harm van Marwijk

Review | 13th December 2018
Insulin translates unfavourable lifestyle into obesity
Hubert Kolb, Michael Stumvoll, Werner Kramer, Kerstin Kempf. and Stephan Martin

Source: Google analytics

Review | 5th May 2016
Cancer immunotherapy: the beginning of the end of cancer?
Sofia Farkona, Eleftherios P. Diamandis and Ivan M. Blasutig

Correspondence | 4th January 2016
Cancer and fertility preservation: international recommendations from an expert meeting
Matteo Lambertini, Lucia Del Mastro, Maria C. Pescio, Claus Y. Andersen, Hatem A. Azim Jr., Fedro A. Peccatori, Mauro Costa, Alberto Revelli, Francesca Salvagno, Alessandra Gennari, Filippo M. Ubaldi, Giovanni B. La Sala, Cristofaro De Stefano, W. Hamish Wallace, Ann H. Partridge and Paola Anserini

Review | 23rd March 2016
The impact of migration on tuberculosis epidemiology and control in high-income countries: a review
Manish Pareek, Christina Greenaway, Teymur Noori, Jose Munoz and Dominik Zenner

Research Article | 4 February 2016
Post-marketing withdrawal of 462 medicinal products because of adverse drug reactions: a systematic review of the world literature
Igho J. Onakpoya, Carl J. Heneghan and Jeffrey K. Aronson

Guideline | 9 November 2016
Effective and safe proton pump inhibitor therapy in acid-related diseases – A position paper addressing benefits and potential harms of acid suppression
Carmelo Scarpignato, Luigi Gatta, Angelo Zullo, Corrado Blandizzi, for the SIF-AIGO-FIMMG Group and on behalf of the Italian Society of Pharmacology, the Italian Association of Hospital Gastroenterologists, and the Italian Federation of General Practitioners

Source: Web of Science

Correspondence | 24 March 2010
CONSORT 2010 Statement: updated guidelines for reporting parallel group randomised trials
Kenneth F Schulz, Douglas G Altman and David Moher

Debate | 14 May 2013
Toward the future of psychiatric diagnosis: the seven pillars of RDoC
Bruce N Cuthbert and Thomas R Insel

Research Article | 26 December 2006
Collagen reorganization at the tumor-stromal interface facilitates local invasion
Paolo P Provenzano, Kevin W Eliceiri, Jay M Campbell, David R Inman, John G White and Patricia J Keely

Research Article | 24 June 2008
miR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cells
Joachim Silber, Daniel A Lim, Claudia Petritsch, Anders I Persson, Alika K Maunakea, Mamie Yu, Scott R Vandenberg, David G Ginzinger, C David James, Joseph F Costello, Gabriele Bergers, William A Weiss, Arturo Alvarez-Buylla and J Graeme Hodgson

Research Article | 26 July 2011
Cross-national epidemiology of DSM-IV major depressive episode
Evelyn Bromet, Laura Helena Andrade, Irving Hwang, Nancy A Sampson, Jordi Alonso, Giovanni de Girolamo, Ron de Graaf, Koen Demyttenaere, Chiyi Hu, Noboru Iwata, Aimee N Karam, Jagdish Kaur, Stanislav Kostyuchenko, Jean-Pierre Lépine, Daphna Levinson, Herbert Matschinger, Maria Elena Medina Mora, Mark Oakley Browne, Jose Posada-Villa, Maria Carmen Viana, David R Williams and Ronald C Kessler

Source Web of Science

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Article collections

Article collection
Beyond Big Data to new Biomedical and Health Data Science: moving to next century precision health

Guest editors: Prof. Aziz Sheikh, Dr. Paul Wicks, Dr. Josip Car and Dr. Marc S. Williams

Article collection
Collection on: Stigma Research and Global Health
Guest editors: Dr. Gretchen Birbeck, Dr. Virginia Bond, Dr. Valerie Earnshaw, Mr. Musah Lumumba El-Nasoor

Article collection
Celebrating the past 15 years of medicine: BMC Medicine anniversary articles

See all article collections here.

Call for papers

New Frontiers in Diagnosis, Treatment and Management of Neuromuscular Disorders
Guest edited by Dr Bradley Turner

Cardiovascular issues in underrepresented populations
Guest edited by Prof Deborah Lawlor, Prof Naveed Sattar, Prof Aletta E Schutte

Complexity in Mental Health Research: Theory, Method, and Empirical Contributions
Guest edited by Dr Eiko I. Fried and Dr Donald Robinaugh

See all our call for papers here.

Reviews and comments

Read our new content commissioned by BMC Medicine editors from leading researchers:

Reviews
Comments (including commentaries, editorials, opinion and debate articles)

Focus: Cancer

Read the latest papers on the cancer across BMC flagship journals.

Tissue-infiltrating lymphocytes signature predicts survival in patients with early/intermediate stage hepatocellular carcinoma​​​​​​
Meng-Xin Tian, Wei-Ren Liu, Han Wang, Yu-Fu Zhou, Lei Jin, Xi-Fei Jiang, Chen-Yang Tao, Zheng Tang, Pei-Yun Zhou, Yuan Fang, Wei-Feng Qu, Zhen-Bin Ding, Yuan-Fei Peng, Zhi Dai, Shuang-Jian Qiu, Jian Zhou, Wan Yee Lau, Jia Fan & Ying-Hong Shi
Published in BMC Medicine 05 June 2019

VOPP1 promotes breast tumorigenesis by interacting with the tumor suppressor WWOX

Florian Bonin, Karim Taouis, Paula Azorin, Ambre Petitalot, Zakia Tariq, Sebastien Nola, Nadège Bouteille, Sandrine Tury, Sophie Vacher, Ivan Bièche, Khadija Ait Rais, Gaelle Pierron, Laetitia Fuhrmann, Anne Vincent-Salomon, Etienne Formstecher, Jacques Camonis, Rosette Lidereau, François Lallemand & Keltouma Driouch 

Published in BMC Biology 02 October 2018

Time series analysis of neoadjuvant chemotherapy and bevacizumab-treated breast carcinomas reveals a systemic shift in genomic aberrations​​​​​​​
Elen Kristine Höglander, Silje Nord, David C. Wedge, Ole Christian Lingjærde, Laxmi Silwal-Pandit, Hedda vdL Gythfeldt, Hans Kristian Moen Vollan, Thomas Fleischer, Marit Krohn, EllenSchlitchting, Elin Borgen, Øystein Garred, Marit M. Holmen, Erik Wist, Bjørn Naume, Peter Van Loo, Anne-Lise Børresen-Dale, Olav Engebraaten & Vessela Kristensen
Published in Genome Medicine 29 November 2019

VULCAN integrates ChIP-seq with patient-derived co-expression networks to identify GRHL2 as a key co-regulator of ERa at enhancers in breast cancer
Andrew N. Holding, Federico M. Giorgi, Amanda Donnelly, Amy E. Cullen, Sankari Nagarajan, Luke A. Selth & Florian Markowetz 
Published in Genome Biology 13 May 2019

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