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Article collection: Beyond Big Data to new Biomedical and Health Data Science: moving to next century precision health

We are pleased to launch our new collection which provides examples on how big-data driven approaches might ultimately improve health outcomes and addresses data complexity, challenges facing this type of research, and other enablers and barriers. 

Research: Modelling the case for a universal hepatitis C vaccine

Using a mathematical model, researchers examined the potential impact of a hepatitis C vaccine on the feasibility and cost of achieving and 80% reduction in hepatitis C incidence by 2030, finding that many countries could achieve this reduction if a 75% efficacious vaccine with a 10-year duration of protection were available, and in a cost-effective manner, strongly supporting the case for hepatitis C vaccine development as an urgent public health need.

Research: Immunity levels for measles elimination

A modeling study determined age-specific immunity levels to ensure measles elimination, concluding levels needed for measles eradication are higher than previously estimated, suggesting school entry provides an opportunity to ensure sufficient vaccination coverage.

Correspondence: Fifteen years of epidemiology in BMC Medicine

Editorial Board Member Deborah Lawlor looks at how changes in the field of epidemiology are reflected in BMC Medicine’s publications over the past 15 years; discusses the potential of a triangulation framework for determining causality; and stresses the value of data sharing.

Aims and scope

BMC Medicine is the flagship medical journal of the BMC series. An open access, open peer-reviewed general medical journal, BMC Medicine publishes outstanding and influential research in all areas of clinical practice, translational medicine, medical and health advances, public health, global health, policy, and general topics of interest to the biomedical and sociomedical professional communities. We also publish stimulating debates and reviews as well as unique forum articles and concise tutorials.  

Articles

  1. Content type: Research article

      |  

    Authors: Tobias Klatte, Kevin M. Gallagher, Luca Afferi, Alessandro Volpe, Nils Kroeger, Silvia Ribback, Alan McNeill, Antony C. P. Riddick, James N. Armitage, Tevita F. ‘Aho, Tim Eisen, Kate Fife, Axel Bex, Allan J. Pantuck and Grant D. Stewart

Most accessed (recent)

Research article | 29th November 2018
Sauna bathing is associated with reduced cardiovascular mortality and improves risk prediction in men and women: a prospective cohort study
Tanjaniina Laukkanen, Setor K. Kunutsor, Hassan Khan, Peter Willeit, Francesco Zaccardi and Jari A. Laukkanen
 

Research article | 11th January 2019
Morbidity, mortality and missed appointments in healthcare: a national retrospective data linkage study
Ross McQueenie, David A. Ellis, Alex McConnachie, Philip Wilson and Andrea E. Williamson

Research article | 10th January 2019
The impact of repeated vaccination on influenza vaccine effectiveness: a systematic review and meta-analysis
Lauren C. Ramsay, Sarah A. Buchan, Robert G. Stirling, Benjamin J. Cowling, Shuo Feng, Jeffrey C. Kwong and Bryna F. Warshawsky

Research article | 15th January 2019
Serious adverse events reported in placebo randomised controlled trials of oral naltrexone: a systematic review and meta-analysis
Monica Bolton, Alex Hodkinson, Shivani Boda, Alan Mould, Maria Panagioti, Sarah Rhodes, Lisa Riste and Harm van Marwijk

Review | 13th December 2018
Insulin translates unfavourable lifestyle into obesity
Hubert Kolb, Michael Stumvoll, Werner Kramer, Kerstin Kempf. and Stephan Martin

Source: Google analytics

Review | 5th May 2016
Cancer immunotherapy: the beginning of the end of cancer?
Sofia Farkona, Eleftherios P. Diamandis and Ivan M. Blasutig

Correspondence | 4th January 2016
Cancer and fertility preservation: international recommendations from an expert meeting
Matteo Lambertini, Lucia Del Mastro, Maria C. Pescio, Claus Y. Andersen, Hatem A. Azim Jr., Fedro A. Peccatori, Mauro Costa, Alberto Revelli, Francesca Salvagno, Alessandra Gennari, Filippo M. Ubaldi, Giovanni B. La Sala, Cristofaro De Stefano, W. Hamish Wallace, Ann H. Partridge and Paola Anserini

Review | 23rd March 2016
The impact of migration on tuberculosis epidemiology and control in high-income countries: a review
Manish Pareek, Christina Greenaway, Teymur Noori, Jose Munoz and Dominik Zenner

Research Article | 4 February 2016
Post-marketing withdrawal of 462 medicinal products because of adverse drug reactions: a systematic review of the world literature
Igho J. Onakpoya, Carl J. Heneghan and Jeffrey K. Aronson

Guideline | 9 November 2016
Effective and safe proton pump inhibitor therapy in acid-related diseases – A position paper addressing benefits and potential harms of acid suppression
Carmelo Scarpignato, Luigi Gatta, Angelo Zullo, Corrado Blandizzi, for the SIF-AIGO-FIMMG Group and on behalf of the Italian Society of Pharmacology, the Italian Association of Hospital Gastroenterologists, and the Italian Federation of General Practitioners

Source: Web of Science

Correspondence | 24 March 2010
CONSORT 2010 Statement: updated guidelines for reporting parallel group randomised trials
Kenneth F Schulz, Douglas G Altman and David Moher

Debate | 14 May 2013
Toward the future of psychiatric diagnosis: the seven pillars of RDoC
Bruce N Cuthbert and Thomas R Insel

Research Article | 26 December 2006
Collagen reorganization at the tumor-stromal interface facilitates local invasion
Paolo P Provenzano, Kevin W Eliceiri, Jay M Campbell, David R Inman, John G White and Patricia J Keely

Research Article | 24 June 2008
miR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cells
Joachim Silber, Daniel A Lim, Claudia Petritsch, Anders I Persson, Alika K Maunakea, Mamie Yu, Scott R Vandenberg, David G Ginzinger, C David James, Joseph F Costello, Gabriele Bergers, William A Weiss, Arturo Alvarez-Buylla and J Graeme Hodgson

Research Article | 26 July 2011
Cross-national epidemiology of DSM-IV major depressive episode
Evelyn Bromet, Laura Helena Andrade, Irving Hwang, Nancy A Sampson, Jordi Alonso, Giovanni de Girolamo, Ron de Graaf, Koen Demyttenaere, Chiyi Hu, Noboru Iwata, Aimee N Karam, Jagdish Kaur, Stanislav Kostyuchenko, Jean-Pierre Lépine, Daphna Levinson, Herbert Matschinger, Maria Elena Medina Mora, Mark Oakley Browne, Jose Posada-Villa, Maria Carmen Viana, David R Williams and Ronald C Kessler

Source Web of Science

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Article collections

Article collection
Beyond Big Data to new Biomedical and Health Data Science: moving to next century precision health

Guest editors: Prof. Aziz Sheikh, Dr. Paul Wicks, Dr. Josip Car and Dr. Marc S. Williams

Article collection
Collection on: Stigma Research and Global Health
Guest editors: Dr. Gretchen Birbeck, Dr. Virginia Bond, Dr. Valerie Earnshaw, Mr. Musah Lumumba El-Nasoor

Article collection
Celebrating the past 15 years of medicine: BMC Medicine anniversary articles

See all article collections here.

Call for papers

New Frontiers in Diagnosis, Treatment and Management of Neuromuscular Disorders
Guest edited by Dr Bradley Turner

Cardiovascular issues in underrepresented populations
Guest edited by Prof Deborah Lawlor, Prof Naveed Sattar, Prof Aletta E Schutte

Complexity in Mental Health Research: Theory, Method, and Empirical Contributions
Guest edited by Dr Eiko I. Fried and Dr Donald Robinaugh

See all our call for papers here.

Reviews and comments

Read our new content commissioned by BMC Medicine editors from leading researchers:

Reviews
Comments (including commentaries, editorials, opinion and debate articles)

Focus: Neurology in Health and Disease

Read the latest papers on Neurology across BMC flagship journals.

Clinical and cost-effectiveness of contingency management for cannabis use in early psychosis: the CIRCLE randomised clinical trial​​​​​​
Luke Sheridan Rains, Louise Marston, Mark Hinton, Steven Marwaha, Thomas Craig, David Fowler, Michael King, Rumana Z. Omar, Paul McCrone, Jonathan Spencer, Joanne Taylor, Sophie Colman, Catherine Harder, Eleanor Gilbert, Amie Randhawa, Kirsty Labuschagne, Charlotte Jones, Theodora Stefanidou, Marina Christoforou, Meghan Craig, John Strang, Tim Weaver & Sonia Johnson

Published in BMC Medicine 15 August 2019

Parkinson’s disease-linked Parkin mutations impair glutamatergic signaling in hippocampal neurons
Mei Zhu, Giuseppe P. Cortese & Clarissa L. Waites

Published in BMC Biology 10 September 2018

Red blood cell indices and anaemia as causative factors for cognitive function deficits and for Alzheimer’s disease
Laura M. Winchester, John Powell, Simon Lovestone & Alejo J. Nevado-Holgado

Published in Genome Medicine 28 June 2018

Detection of circular RNA expression and related quantitative trait loci in the human dorsolateral prefrontal cortex​​​​​​​
Zelin Liu, Yuan Ran, Changyu Tao, Sichen Li, Jian Chen & Ence Yang

Published in Genome Biology 20 May 2019

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