BMC Medicine

Article collection: Beyond Big Data to new Biomedical and Health Data Science: moving to next century precision health

We are pleased to launch our new collection which provides examples on how big-data driven approaches might ultimately improve health outcomes and addresses data complexity, challenges facing this type of research, and other enablers and barriers.

Research: Automated versus physician assignment of cause of death for verbal autopsies

Verbal autopsies with physician assignment of cause of death (COD) are common in resource-limited settings, a randomized controlled trial in India concludes that automated algorithms need additional development and evaluation, before replacing physician assignment.

Research: Suicide attempts in US adults with lifetime DSM-5 eating disorders

Utilizing a nationally representative sample of US adults, this study found that adults with a lifetime diagnosis of eating disorders (anorexia nervosa, bulimia nervosa, or binge eating disorder) using DSM-5 are at greater risk for suicide attempts.

Opinion: Optimising trial designs for antibiotic treatment durations

An opinion article argues that numerous factors need to be considered when deciding which design is best in identifying optimal antibiotic treatment duration, concluding multi-arm trial designs could provide more information compared to traditional head-to-head comparisons.

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Aims and scope

BMC Medicine is the flagship medical journal of the BMC series. An open access, open peer-reviewed general medical journal, BMC Medicine publishes outstanding and influential research in all areas of clinical practice, translational medicine, medical and health advances, public health, global health, policy, and general topics of interest to the biomedical and sociomedical professional communities. We also publish stimulating debates and reviews as well as unique forum articles and concise tutorials.

Articles

Content type: Research article
| 22 July 2019

Low serum IGF1 is associated with hypertension and predicts early cardiovascular events in women with rheumatoid arthritis

Authors: Malin C. Erlandsson, Lovisa Lyngfelt, N. David Åberg, Caroline Wasén, Rachelle A. Espino, Sofia Töyrä Silfverswärd, Mitra Nadali, Katharina Jood, Karin M.E. Andersson, Rille Pullerits and Maria I. Bokarewa
Content type: Research article
| 19 July 2019

Distinct mortality patterns at 0–2 days versus the remaining neonatal period: results from population-based assessment in the Indian state of Bihar

Authors: Rakhi Dandona, G. Anil Kumar, Debarshi Bhattacharya, Md. Akbar, Yamini Atmavilas, Priya Nanda and Lalit Dandona
Content type: Research article
| 18 July 2019

Health professions digital education on clinical practice guidelines: a systematic review by Digital Health Education collaboration

Authors: Lorainne Tudor Car, Aijia Soong, Bhone Myint Kyaw, Kee Leng Chua, Naomi Low-Beer and Azeem Majeed
Content type: Editorial
| 17 July 2019

Beyond the hype of big data and artificial intelligence: building foundations for knowledge and wisdom

Authors: Josip Car, Aziz Sheikh, Paul Wicks and Marc S. Williams
Content type: Opinion
| 17 July 2019

Building the case for actionable ethics in digital health research supported by artificial intelligence

Authors: Camille Nebeker, John Torous and Rebecca J. Bartlett Ellis

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Most accessed (recent)

Research article | 29th November 2018
Sauna bathing is associated with reduced cardiovascular mortality and improves risk prediction in men and women: a prospective cohort study
Tanjaniina Laukkanen, Setor K. Kunutsor, Hassan Khan, Peter Willeit, Francesco Zaccardi and Jari A. Laukkanen

Research article | 11th January 2019
Morbidity, mortality and missed appointments in healthcare: a national retrospective data linkage study
Ross McQueenie, David A. Ellis, Alex McConnachie, Philip Wilson and Andrea E. Williamson

Research article | 10th January 2019
The impact of repeated vaccination on influenza vaccine effectiveness: a systematic review and meta-analysis
Lauren C. Ramsay, Sarah A. Buchan, Robert G. Stirling, Benjamin J. Cowling, Shuo Feng, Jeffrey C. Kwong and Bryna F. Warshawsky

Research article | 15th January 2019
Serious adverse events reported in placebo randomised controlled trials of oral naltrexone: a systematic review and meta-analysis
Monica Bolton, Alex Hodkinson, Shivani Boda, Alan Mould, Maria Panagioti, Sarah Rhodes, Lisa Riste and Harm van Marwijk

Review | 13th December 2018
Insulin translates unfavourable lifestyle into obesity
Hubert Kolb, Michael Stumvoll, Werner Kramer, Kerstin Kempf. and Stephan Martin

_{Source: Google analytics}

_{Review | 5th May 2016}
Cancer immunotherapy: the beginning of the end of cancer?
_{Sofia Farkona, Eleftherios P. Diamandis and Ivan M. Blasutig}

_{Correspondence | 4th January 2016}
Cancer and fertility preservation: international recommendations from an expert meeting
_{Matteo Lambertini, Lucia Del Mastro, Maria C. Pescio, Claus Y. Andersen, Hatem A. Azim Jr., Fedro A. Peccatori, Mauro Costa, Alberto Revelli, Francesca Salvagno, Alessandra Gennari, Filippo M. Ubaldi, Giovanni B. La Sala, Cristofaro De Stefano, W. Hamish Wallace, Ann H. Partridge and Paola Anserini}

_{Review | 23rd March 2016}
The impact of migration on tuberculosis epidemiology and control in high-income countries: a review
_{Manish Pareek, Christina Greenaway, Teymur Noori, Jose Munoz and Dominik Zenner}

_{Research Article | 4 February 2016}
Post-marketing withdrawal of 462 medicinal products because of adverse drug reactions: a systematic review of the world literature
_{Igho J. Onakpoya, Carl J. Heneghan and Jeffrey K. Aronson}

_{Guideline | 9 November 2016}
Effective and safe proton pump inhibitor therapy in acid-related diseases – A position paper addressing benefits and potential harms of acid suppression
_{Carmelo Scarpignato, Luigi Gatta, Angelo Zullo, Corrado Blandizzi, for the SIF-AIGO-FIMMG Group and on behalf of the Italian Society of Pharmacology, the Italian Association of Hospital Gastroenterologists, and the Italian Federation of General Practitioners}

_{Source: Web of Science}

_{Correspondence | 24 March 2010}
CONSORT 2010 Statement: updated guidelines for reporting parallel group randomised trials
_{Kenneth F Schulz, Douglas G Altman and David Moher}

_{Debate | 14 May 2013}
Toward the future of psychiatric diagnosis: the seven pillars of RDoC
_{Bruce N Cuthbert and Thomas R Insel}

_{Research Article | 26 December 2006}
Collagen reorganization at the tumor-stromal interface facilitates local invasion
_{Paolo P Provenzano, Kevin W Eliceiri, Jay M Campbell, David R Inman, John G White and Patricia J Keely}

_{Research Article | 24 June 2008}
miR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cells
_{Joachim Silber, Daniel A Lim, Claudia Petritsch, Anders I Persson, Alika K Maunakea, Mamie Yu, Scott R Vandenberg, David G Ginzinger, C David James, Joseph F Costello, Gabriele Bergers, William A Weiss, Arturo Alvarez-Buylla and J Graeme Hodgson}

_{Research Article | 26 July 2011}
Cross-national epidemiology of DSM-IV major depressive episode
_{Evelyn Bromet, Laura Helena Andrade, Irving Hwang, Nancy A Sampson, Jordi Alonso, Giovanni de Girolamo, Ron de Graaf, Koen Demyttenaere, Chiyi Hu, Noboru Iwata, Aimee N Karam, Jagdish Kaur, Stanislav Kostyuchenko, Jean-Pierre Lépine, Daphna Levinson, Herbert Matschinger, Maria Elena Medina Mora, Mark Oakley Browne, Jose Posada-Villa, Maria Carmen Viana, David R Williams and Ronald C Kessler}

_{Source Web of Science}

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Article collections

Article collection
Beyond Big Data to new Biomedical and Health Data Science: moving to next century precision health
Guest editors: Prof. Aziz Sheikh, Dr. Paul Wicks, Dr. Josip Car and Dr. Marc S. Williams

Article collection
Collection on: Stigma Research and Global Health
Guest editors: Dr. Gretchen Birbeck, Dr. Virginia Bond, Dr. Valerie Earnshaw, Mr. Musah Lumumba El-Nasoor

Article collection
Celebrating the past 15 years of medicine: BMC Medicine anniversary articles

See all article collections here.

Call for papers

New Frontiers in Diagnosis, Treatment and Management of Neuromuscular Disorders
Guest edited by Dr Bradley Turner

Cardiovascular issues in underrepresented populations
Guest edited by Prof Deborah Lawlor, Prof Naveed Sattar, Prof Aletta E Schutte

Complexity in Mental Health Research: Theory, Method, and Empirical Contributions
Guest edited by Dr Eiko I. Fried and Dr Donald Robinaugh

See all our call for papers here.

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Reviews and comments

Read our new content commissioned by BMC Medicine editors from leading researchers:

Reviews
Comments (including commentaries, editorials, opinion and debate articles)

Focus: Immunology in Health and Disease

Read the latest papers on immunology across BMC flagship journals.

A step beyond the hygiene hypothesis—immune-mediated classes determined in a population-based study
Vladeta Ajdacic-Gross, Margot Mutsch, Stephanie Rodgers, Anja Tesic, Mario Müller, Erich Seifritz, En-Young N. Wagner, Roland von Känel, Markus A. Landolt, Nina Steinemann, Viktor von Wyl, Enrique Castelao, Marie-Pierre F. Strippoli, Jennifer Glaus, Caroline Vandeleur, Pedro M. Marques-Vidal, Peter Vollenweider and Martin Preisig
Published in BMC Medicine on: 9 April 2019

Time-resolved transcriptome and proteome landscape of human regulatory T cell (Treg) differentiation reveals novel regulators of FOXP3
Angelika Schmidt, Francesco Marabita, Narsis A. Kiani, Catharina C. Gross, Henrik J. Johansson, Szabolcs Éliás, Sini Rautio, Matilda Eriksson, Sunjay Jude Fernandes, Gilad Silberberg, Ubaid Ullah, Urvashi Bhatia, Harri Lähdesmäki, Janne Lehtiö, David Gomez-Cabrero, Heinz Wiendl, Riitta Lahesmaa and Jesper Tegnér
Published in BMC Biology on: 7 May 2018

Single-cell transcriptomics reveal that PD-1 mediates immune tolerance by regulating proliferation of regulatory T cells
Cherry S. Leung, Kevin Y. Yang, Xisheng Li, Vicken W. Chan, Manching Ku, Herman Waldmann, Shohei Hori, Jason C. H. Tsang, Yuk Ming Dennis Lo and Kathy O. Lui
Published in Genome Medicine on: 20 September 2018

Exploring the genetic basis of human population differences in DNA methylation and their causal impact on immune gene regulation
Lucas T. Husquin, Maxime Rotival, Maud Fagny, Hélène Quach, Nora Zidane, Lisa M. McEwen, Julia L. MacIsaac, Michael S. Kobor, Hugues Aschard, Etienne Patin and Lluis Quintana-Murci
Published in Genome Biology on: 18 December 2018

BMC Medicine

Article collection: Beyond Big Data to new Biomedical and Health Data Science: moving to next century precision health

Research: Automated versus physician assignment of cause of death for verbal autopsies

Research: Suicide attempts in US adults with lifetime DSM-5 eating disorders

Opinion: Optimising trial designs for antibiotic treatment durations

BMC Medicine Early Career Researcher (ECR) Survey

Aims and scope

Articles

Low serum IGF1 is associated with hypertension and predicts early cardiovascular events in women with rheumatoid arthritis

Distinct mortality patterns at 0–2 days versus the remaining neonatal period: results from population-based assessment in the Indian state of Bihar

Health professions digital education on clinical practice guidelines: a systematic review by Digital Health Education collaboration

Beyond the hype of big data and artificial intelligence: building foundations for knowledge and wisdom

Building the case for actionable ethics in digital health research supported by artificial intelligence

Most accessed (recent)

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Call for papers

From the blog

Three questions answered by the winners of the BMC ‘Cancer Awareness’ poetry competition

BMC Medicine attends the International Association of Gerontology and Geriatrics European Region (IAGG-ER) Congress 2019 meeting

The “No jab, no school” policy and vaccination efforts needed for measles elimination

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Focus: Immunology in Health and Disease

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