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  1. Understanding of the role of ethnicity and socioeconomic position in the risk of developing SARS-CoV-2 infection is limited. We investigated this in the UK Biobank study.

    Authors: Claire L. Niedzwiedz, Catherine A. O’Donnell, Bhautesh Dinesh Jani, Evangelia Demou, Frederick K. Ho, Carlos Celis-Morales, Barbara I. Nicholl, Frances S. Mair, Paul Welsh, Naveed Sattar, Jill P. Pell and S. Vittal Katikireddi

    Citation: BMC Medicine 2020 18:160

    Content type: Research article

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  2. Choosing or altering the planned statistical analysis approach after examination of trial data (often referred to as ‘p-hacking’) can bias the results of randomised trials. However, the extent of this issue in...

    Authors: Suzie Cro, Gordon Forbes, Nicholas A. Johnson and Brennan C. Kahan

    Citation: BMC Medicine 2020 18:137

    Content type: Research article

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  3. The five-tiered Cambridge Prognostic Group (CPG) classification is a better predictor of prostate cancer-specific mortality than the traditional three-tiered classification (low, intermediate, and high risk). ...

    Authors: M. G. Parry, T. E. Cowling, A. Sujenthiran, J. Nossiter, B. Berry, P. Cathcart, A. Aggarwal, H. Payne, J. van der Meulen, N. W. Clarke and V. J. Gnanapragasam

    Citation: BMC Medicine 2020 18:114

    Content type: Research article

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  4. Serum free thiols (R-SH, sulfhydryl groups) reliably reflect systemic oxidative stress. Since serum free thiols are rapidly oxidized by reactive species, systemic oxidative stress is generally associated with ...

    Authors: Amaal E. Abdulle, Arno R. Bourgonje, Lyanne M. Kieneker, Anne M. Koning, S. la Bastide-van Gemert, Marian L. C. Bulthuis, Gerard Dijkstra, Klaas Nico Faber, Robin P. F. Dullaart, Stephan J. L. Bakker, Reinold O. B. Gans, Ron T. Gansevoort, Douwe J. Mulder, Andreas Pasch and Harry van Goor

    Citation: BMC Medicine 2020 18:130

    Content type: Research article

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  5. Particulate matter exposure during in utero life may entail adverse health outcomes later in life. The microvasculature undergoes extensive, organ-specific prenatal maturation. A growing body of evidence shows th...

    Authors: Leen J. Luyten, Yinthe Dockx, Eline B. Provost, Narjes Madhloum, Hanne Sleurs, Kristof Y. Neven, Bram G. Janssen, Hannelore Bové, Florence Debacq-Chainiaux, Nele Gerrits, Wouter Lefebvre, Michelle Plusquin, Charlotte Vanpoucke, Patrick De Boever and Tim S. Nawrot

    Citation: BMC Medicine 2020 18:128

    Content type: Research article

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  6. Individuals with co-occurring hyperactivity disorder/hyperactivity disorder (ADHD) and autism spectrum disorder (ASD) can have complex presentations that may complicate diagnosis and treatment. There are estab...

    Authors: Susan Young, Jack Hollingdale, Michael Absoud, Patrick Bolton, Polly Branney, William Colley, Emily Craze, Mayuri Dave, Quinton Deeley, Emad Farrag, Gisli Gudjonsson, Peter Hill, Ho-lan Liang, Clodagh Murphy, Peri Mackintosh, Marianna Murin…

    Citation: BMC Medicine 2020 18:146

    Content type: Guideline

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  7. Fetuses affected by placental insufficiency do not receive adequate nutrients and oxygenation, become growth restricted and acidemic, and can demise. Preterm fetal growth restriction is a severe form of placen...

    Authors: Natalie J. Hannan, Owen Stock, Rebecca Spencer, Clare Whitehead, Anna L. David, Katie Groom, Scott Petersen, Amanda Henry, Joanne M. Said, Sean Seeho, Stefan C. Kane, Lavinia Gordon, Sally Beard, Kantaraja Chindera, Smita Karegodar, Richard Hiscock…

    Citation: BMC Medicine 2020 18:145

    Content type: Research article

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  8. Antimicrobial resistance is driven by the overuse of antibiotics. This study aimed to develop and validate clinical prediction models for the risk of infection-related hospital admission with upper respiratory...

    Authors: Chirag Mistry, Victoria Palin, Yan Li, Glen P. Martin, David Jenkins, William Welfare, Darren M. Ashcroft and Tjeerd van Staa

    Citation: BMC Medicine 2020 18:118

    Content type: Research article

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  9. Reconfiguration of urgent and emergency care services often increases travel time/distance for patients to reach an appropriate facility. Evidence of the effects of reconfiguration is important for local commu...

    Authors: Duncan Chambers, Anna Cantrell, Susan Baxter, Janette Turner and Andrew Booth

    Citation: BMC Medicine 2020 18:117

    Content type: Research article

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  10. Cardiovascular Risk Factors, Aging, and Incidence of Dementia (CAIDE) risk score is the only currently available midlife risk score for dementia. We compared CAIDE to Framingham cardiovascular Risk Score (FRS)...

    Authors: Aurore Fayosse, Dinh-Phong Nguyen, Aline Dugravot, Julien Dumurgier, Adam G. Tabak, Mika Kivimäki, Séverine Sabia and Archana Singh-Manoux

    Citation: BMC Medicine 2020 18:107

    Content type: Research article

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  11. Research is fundamental to high-quality care, but concerns have been raised about whether health research is conducted in the populations most affected by high disease prevalence. Geographical distribution of ...

    Authors: Peter Bower, Christos Grigoroglou, Laura Anselmi, Evangelos Kontopantelis, Matthew Sutton, Mark Ashworth, Philip Evans, Stephen Lock, Stephen Smye and Kathryn Abel

    Citation: BMC Medicine 2020 18:133

    Content type: Research article

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  12. The increase in the number of predatory journals puts scholarly communication at risk. In order to guard against publication in predatory journals, authors may use checklists to help detect predatory journals....

    Authors: Samantha Cukier, Lucas Helal, Danielle B. Rice, Justina Pupkaite, Nadera Ahmadzai, Mitchell Wilson, Becky Skidmore, Manoj M. Lalu and David Moher

    Citation: BMC Medicine 2020 18:104

    Content type: Research article

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    The Commentary to this article has been published in BMC Medicine 2020 18:125

  13. Opioid overdoses have had a serious impact on the public health systems and socioeconomic welfare of several countries. Within this broader context, we focus our study on primary care opioid prescribing in Eng...

    Authors: Rossano Schifanella, Dario Delle Vedove, Alberto Salomone, Paolo Bajardi and Daniela Paolotti

    Citation: BMC Medicine 2020 18:127

    Content type: Research Article

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  14. Medical schools differ, particularly in their teaching, but it is unclear whether such differences matter, although influential claims are often made. The Medical School Differences (MedDifs) study brings togethe...

    Authors: I. C. McManus, Andrew Christopher Harborne, Hugo Layard Horsfall, Tobin Joseph, Daniel T. Smith, Tess Marshall-Andon, Ryan Samuels, Joshua William Kearsley, Nadine Abbas, Hassan Baig, Joseph Beecham, Natasha Benons, Charlie Caird, Ryan Clark, Thomas Cope, James Coultas…

    Citation: BMC Medicine 2020 18:136

    Content type: Research article

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  15. What subjects UK medical schools teach, what ways they teach subjects, and how much they teach those subjects is unclear. Whether teaching differences matter is a separate, important question. This study provides...

    Authors: Oliver Patrick Devine, Andrew Christopher Harborne, Hugo Layard Horsfall, Tobin Joseph, Tess Marshall-Andon, Ryan Samuels, Joshua William Kearsley, Nadine Abbas, Hassan Baig, Joseph Beecham, Natasha Benons, Charlie Caird, Ryan Clark, Thomas Cope, James Coultas, Luke Debenham…

    Citation: BMC Medicine 2020 18:126

    Content type: Research article

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  16. Physical activity (PA) increases a person’s inhalation of air pollutants due to greater ventilation, possibly leading to larger adverse health effects. This study aims to investigate the combined effects of lo...

    Authors: Cui Guo, Yacong Bo, Ta-Chien Chan, Zilong Zhang, Changqing Lin, Tony Tam, Alexis K. H. Lau, Ly-yun Chang, Gerard Hoek and Xiang Qian Lao

    Citation: BMC Medicine 2020 18:134

    Content type: Research article

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  17. Early-life malnutrition may have long-lasting effects on microbe-host interactions that affect health and disease susceptibility later in life. Diet quality and quantity in conjunction with toxin and pathogen ...

    Authors: Andrew J. Forgie, Kelsea M. Drall, Stephane L. Bourque, Catherine J. Field, Anita L. Kozyrskyj and Benjamin P. Willing

    Citation: BMC Medicine 2020 18:135

    Content type: Review

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  18. Actigraphy has received increasing attention in classifying rest-activity cycles. However, in patients with disorders of consciousness (DOC), actigraphy data may be considerably confounded by passive movements...

    Authors: Monika Angerer, Manuel Schabus, Marion Raml, Gerald Pichler, Alexander B. Kunz, Monika Scarpatetti, Eugen Trinka and Christine Blume

    Citation: BMC Medicine 2020 18:106

    Content type: Correspondence

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  19. A Target Product Profile (TPP) outlines the necessary characteristics of an innovative product to address an unmet clinical need. TPPs could be used to better guide manufacturers in the development of ‘fit for...

    Authors: Paola Cocco, Anam Ayaz-Shah, Michael Paul Messenger, Robert Michael West and Bethany Shinkins

    Citation: BMC Medicine 2020 18:119

    Content type: Research article

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  20. Nearly a third of children in the UK are overweight, with the prevalence in the most deprived areas more than twice that in the least deprived. The aim was to develop a risk identification model for childhood ...

    Authors: Nida Ziauddeen, Sam Wilding, Paul J. Roderick, Nicholas S. Macklon, Dianna Smith, Debbie Chase and Nisreen A. Alwan

    Citation: BMC Medicine 2020 18:105

    Content type: Research article

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  21. Many decisions regarding health resource utilization flow through the patient-clinician interaction. Thus, it represents a place where de-implementation interventions may have considerable effect on reducing t...

    Authors: Emma E. Sypes, Chloe de Grood, Liam Whalen-Browne, Fiona M. Clement, Jeanna Parsons Leigh, Daniel J. Niven and Henry T. Stelfox

    Citation: BMC Medicine 2020 18:116

    Content type: Research article

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  22. To mitigate and slow the spread of COVID-19, many countries have adopted unprecedented physical distancing policies, including the UK. We evaluate whether these measures might be sufficient to control the epid...

    Authors: Christopher I. Jarvis, Kevin Van Zandvoort, Amy Gimma, Kiesha Prem, Petra Klepac, G. James Rubin and W. John Edmunds

    Citation: BMC Medicine 2020 18:124

    Content type: Research article

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  23. Compared to adults, there are relatively few studies on COVID-19 infection in children, and even less focusing on the unique features of COVID-19 in children in terms of laboratory findings, locations of compu...

    Authors: Huijing Ma, Jiani Hu, Jie Tian, Xi Zhou, Hui Li, Maxwell Thomas Laws, Luke David Wesemann, Baiqi Zhu, Wei Chen, Rafael Ramos, Jun Xia and Jianbo Shao

    Citation: BMC Medicine 2020 18:123

    Content type: Research article

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    The Commentary to this article has been published in BMC Medicine 2020 18:158

  24. There is a decreasing trend in the proportion of individuals who perceive e-cigarettes to be less harmful than conventional cigarettes across the UK, Europe and the US. It is important to assess whether this m...

    Authors: Olga Perski, Emma Beard and Jamie Brown

    Citation: BMC Medicine 2020 18:98

    Content type: Research article

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  25. Beta-blockers are widely used for many cardiovascular conditions; however, their efficacy in contemporary clinical practice remains uncertain.

    Authors: Oliver J. Ziff, Monica Samra, James P. Howard, Daniel I. Bromage, Frank Ruschitzka, Darrel P. Francis and Dipak Kotecha

    Citation: BMC Medicine 2020 18:103

    Content type: Research article

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  26. For years, the benefits of septoplasty have been questioned. Due to the scarce and inconclusive literature, several National Health Service (NHS) Clinical Commissioning Groups in England decided to add septal ...

    Authors: M. M. H. T. van Egmond, J. P. C. Grutters, G. Hannink, N. van Heerbeek and M. M. Rovers

    Citation: BMC Medicine 2020 18:101

    Content type: Research article

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  27. Antidepressants may be used to manage a number of conditions in children and young people including depression, anxiety, and obsessive-compulsive disorder. UK guidelines for the treatment of depression in chil...

    Authors: Ruth H. Jack, Rebecca M. Joseph, Carol Coupland, Debbie Butler, Chris Hollis, Richard Morriss, Roger David Knaggs, Andrea Cipriani, Samuele Cortese and Julia Hippisley-Cox

    Citation: BMC Medicine 2020 18:93

    Content type: Research article

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    The Commentary to this article has been published in BMC Medicine 2020 18:150

  28. The most widely used measures of declining burden of malaria across sub-Saharan Africa are predictions from geospatial models. These models apply spatiotemporal autocorrelations and covariates to parasite prev...

    Authors: Alice Kamau, Polycarp Mogeni, Emelda A. Okiro, Robert W. Snow and Philip Bejon

    Citation: BMC Medicine 2020 18:94

    Content type: Research article

    Published on:

  29. Most of the world’s sickle cell disease (SCD) burden is in Africa, where it is a major contributor to child morbidity and mortality. Despite the low cost of many preventive SCD interventions, insufficient reso...

    Authors: Assaf P. Oron, Dennis L. Chao, Echezona E. Ezeanolue, Loveth N. Ezenwa, Frédéric B. Piel, Osifo Telison Ojogun, Sophie Uyoga, Thomas N. Williams and Obiageli E. Nnodu

    Citation: BMC Medicine 2020 18:92

    Content type: Opinion

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  30. The 2018–2019 Ebola virus disease (EVD) outbreak in North Kivu and Ituri provinces in the Democratic Republic of the Congo (DRC) is the largest ever recorded in the DRC. It has been declared a Public Health Em...

    Authors: Moritz U. G. Kraemer, David M. Pigott, Sarah C. Hill, Samantha Vanderslott, Robert C. Reiner Jr, Stephanie Stasse, John S. Brownstein, Bernardo Gutierrez, Francis Dennig, Simon I. Hay, G. R. William Wint, Oliver G. Pybus, Marcia C. Castro, Patrick Vinck, Phuong N. Pham, Eric J. Nilles…

    Citation: BMC Medicine 2020 18:113

    Content type: Research article

    Published on:

  31. Recent efforts to address the obesity epidemic have focused on sugar consumption, especially sugar-sweetened beverages. However, sugar takes many forms, is only one contributor to overall energy consumption an...

    Authors: Jana J. Anderson, Stuart R. Gray, Paul Welsh, Daniel F. Mackay, Carlos A. Celis-Morales, Donald M. Lyall, John Forbes, Naveed Sattar, Jason M. R. Gill and Jill P. Pell

    Citation: BMC Medicine 2020 18:97

    Content type: Research article

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    The Commentary to this article has been published in BMC Medicine 2020 18:112

  32. To reduce inappropriate antibiotic use, public health campaigns often provide fear-based information about antimicrobial resistance (AMR). Meta-analyses have found that fear-based campaigns in other contexts a...

    Authors: Laurence S. J. Roope, Sarah Tonkin-Crine, Natalie Herd, Susan Michie, Koen B. Pouwels, Enrique Castro-Sanchez, Anna Sallis, Susan Hopkins, Julie V. Robotham, Derrick W. Crook, Tim Peto, Michele Peters, Christopher C. Butler, A. Sarah Walker and Sarah Wordsworth

    Citation: BMC Medicine 2020 18:110

    Content type: Research article

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  33. The recent emergence of strains belonging to the meningococcal serogroup W (MenW) sequence type-11 clonal complex and descending from the South American sub-lineage (MenW:cc11/SA) has caused significant shifts...

    Authors: Matthieu Domenech de Cellès, Helen Campbell, Ray Borrow, Muhamed-Kheir Taha and Lulla Opatowski

    Citation: BMC Medicine 2020 18:109

    Content type: Research article

    Published on:

  34. When a journal receives a duplicate publication, the ability to identify the submitted work as previously published, and reject it, is an assay to publication ethics best practices. The aim of this study was t...

    Authors: Kelly D. Cobey, Danielle B. Rice, Manoj M. Lalu, Daniel Abramowitz, Nadera Ahmadzai, Heather Cunningham, Ana Patricia Ayala, Hana Raffoul, Faizan Khan, Larissa Shamseer and David Moher

    Citation: BMC Medicine 2020 18:88

    Content type: Research article

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  35. A number of studies have reported an association between the occurrence of immune-related adverse events (irAEs) and clinical efficacy in patients undergoing treatment with immune checkpoint inhibitors (ICIs),...

    Authors: Xiaoxiang Zhou, Zhuoran Yao, Huaxia Yang, Naixin Liang, Xuan Zhang and Fengchun Zhang

    Citation: BMC Medicine 2020 18:87

    Content type: Research article

    Published on:

    The Commentary to this article has been published in BMC Medicine 2020 18:111

  36. The clinical pathway to detect and diagnose prostate cancer has been revolutionised by the use of multiparametric MRI (mpMRI pre-biopsy). mpMRI however remains a resource-intensive test and is highly operator ...

    Authors: Lois Kim, Nicholas Boxall, Anne George, Keith Burling, Pete Acher, Jonathan Aning, Stuart McCracken, Toby Page and Vincent J. Gnanapragasam

    Citation: BMC Medicine 2020 18:95

    Content type: Research article

    Published on:

  37. Trials have shown total diet replacement (TDR) programmes are safe and effective for weight loss in primary care. However, it is not clear whether participant characteristics affect uptake, attendance, or effe...

    Authors: Nerys M. Astbury, Kate Tudor, Paul Aveyard and Susan A. Jebb

    Citation: BMC Medicine 2020 18:86

    Content type: Research article

    Published on:

  38. Sepsis is a leading cause of death in intensive care units (ICUs), but outcomes of individual patients are difficult to predict. The recently developed clinical metabolomics has been recognized as a promising ...

    Authors: Jing Wang, Yizhu Sun, Shengnan Teng and Kefeng Li

    Citation: BMC Medicine 2020 18:83

    Content type: Research article

    Published on:

  39. China has an aging population with an increasing number of adults aged ≥ 60 years. Influenza causes a heavy disease burden in older adults, but can be alleviated by vaccination. We assessed the cost-effectiven...

    Authors: Juan Yang, Katherine E. Atkins, Luzhao Feng, Marc Baguelin, Peng Wu, Han Yan, Eric H. Y. Lau, Joseph T. Wu, Yang Liu, Benjamin J. Cowling, Mark Jit and Hongjie Yu

    Citation: BMC Medicine 2020 18:90

    Content type: Research article

    Published on:

Announcement: COVID-19 and impact on peer review

As a result of the significant disruption that is being caused by the COVID-19 pandemic we are very aware that many researchers will have difficulty in meeting the timelines associated with our peer review process during normal times.  Please do let us know if you need additional time. Our systems will continue to remind you of the original timelines but we intend to be highly flexible at this time.

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