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  1. Content type: Research article

    Major depressive disorder (MDD) is often handled as an episodic and isolated disorder, resulting in an optimistic view about its prognosis. Herein, we test the idea that the prognosis of MDD changes if we vary...

    Authors: Judith Verduijn, Josine E. Verhoeven, Yuri Milaneschi, Robert A. Schoevers, Albert M. van Hemert, Aartjan T. F. Beekman and Brenda W. J. H. Penninx

    Citation: BMC Medicine 2017 15:215

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  2. Content type: Guideline

    Populations exposed to humanitarian emergencies are particularly vulnerable to mental health problems, including new onset, relapse and deterioration of psychotic disorders. Inadequate care for this group may ...

    Authors: Giovanni Ostuzzi, Corrado Barbui, Charlotte Hanlon, Sudipto Chatterjee, Julian Eaton, Lynne Jones, Derrick Silove and Peter Ventevogel

    Citation: BMC Medicine 2017 15:197

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  3. Content type: Commentary

    This Commentary describes the situation and healthcare needs of Afghans returning to their country of origin. With more than 600,000 Afghans returned from Pakistan and approximately 450,000 Afghans returned fr...

    Authors: Ariel Higgins-Steele, David Lai, Paata Chikvaidze, Khaksar Yousufi, Zelaikha Anwari, Richard Peeperkorn and Karen Edmond

    Citation: BMC Medicine 2017 15:196

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  4. Content type: Research article

    Chronic hepatitis B virus (HBV) infection leads to liver fibrosis, which is a major risk factor in hepatocellular carcinoma (HCC) and an independent risk factor of recurrence after HCC tumor resection. The HBV...

    Authors: Seungyeul Yoo, Wenhui Wang, Qin Wang, M Isabel Fiel, Eunjee Lee, Spiros P. Hiotis and Jun Zhu

    Citation: BMC Medicine 2017 15:214

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  5. Content type: Research article

    Diagnosis of monogenic as well as atypical forms of diabetes mellitus has important clinical implications for their specific diagnosis, prognosis, and targeted treatment. Single gene mutations that affect beta...

    Authors: Vikas Bansal, Johann Gassenhuber, Tierney Phillips, Glenn Oliveira, Rebecca Harbaugh, Nikki Villarasa, Eric J. Topol, Thomas Seufferlein and Bernhard O. Boehm

    Citation: BMC Medicine 2017 15:213

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  6. Content type: Technical advance

    Epigenomes are tissue specific and thus the choice of surrogate tissue can play a critical role in interpreting neonatal epigenome-wide association studies (EWAS) and in their extrapolation to target tissue. T...

    Authors: Xinyi Lin, Ai Ling Teh, Li Chen, Ives Yubin Lim, Pei Fang Tan, Julia L. MacIsaac, Alexander M. Morin, Fabian Yap, Kok Hian Tan, Seang Mei Saw, Yung Seng Lee, Joanna D. Holbrook, Keith M. Godfrey, Michael J. Meaney, Michael S. Kobor, Yap Seng Chong…

    Citation: BMC Medicine 2017 15:211

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  7. Content type: Research article

    Inflammation occurs as an immediate protective response of the immune system to a harmful stimulus, whether locally confined or systemic. In contrast, a persisting, i.e., chronic, inflammatory state, even at a...

    Authors: Maik Pietzner, Anne Kaul, Ann-Kristin Henning, Gabi Kastenmüller, Anna Artati, Markus M. Lerch, Jerzy Adamski, Matthias Nauck and Nele Friedrich

    Citation: BMC Medicine 2017 15:210

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  8. Content type: Research article

    Depression in tuberculosis increases the risk for adverse health outcomes. However, little is known about comorbid depression and tuberculosis in the general population. Thus, we assessed the association betwe...

    Authors: Ai Koyanagi, Davy Vancampfort, André F. Carvalho, Jordan E. DeVylder, Josep Maria Haro, Damiano Pizzol, Nicola Veronese and Brendon Stubbs

    Citation: BMC Medicine 2017 15:209

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  9. Content type: Research article

    Fiscal interventions are promising strategies to improve diets, reduce cardiovascular disease and diabetes (cardiometabolic diseases; CMD), and address health disparities. The aim of this study is to estimate ...

    Authors: José L. Peñalvo, Frederick Cudhea, Renata Micha, Colin D. Rehm, Ashkan Afshin, Laurie Whitsel, Parke Wilde, Tom Gaziano, Jonathan Pearson-Stuttard, Martin O’Flaherty, Simon Capewell and Dariush Mozaffarian

    Citation: BMC Medicine 2017 15:208

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  10. Content type: Research article

    Tuberculosis kills more people than any other infectious disease, and new regimens are essential. The primary endpoint for confirmatory phase III trials for new regimens is a composite outcome that includes ba...

    Authors: Patrick P. J. Phillips, Carl M. Mendel, Andrew J. Nunn, Timothy D. McHugh, Angela M. Crook, Robert Hunt, Anna Bateson and Stephen H. Gillespie

    Citation: BMC Medicine 2017 15:207

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  11. Content type: Research article

    Provision of routine iron supplements to prevent anaemia could increase the risk for lower genital tract infections as virulence of some pathogens depends on iron availability. This trial in Burkina Faso asses...

    Authors: Loretta Brabin, Stephen A. Roberts, Sabine Gies, Andrew Nelson, Salou Diallo, Christopher J. Stewart, Adama Kazienga, Julia Birtles, Sayouba Ouedraogo, Yves Claeys, Halidou Tinto, Umberto d’Alessandro, E. Brian Faragher and Bernard Brabin

    Citation: BMC Medicine 2017 15:206

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  12. Content type: Research article

    Telomere attrition is extremely rapid during the first years of life, while lifestyle during adulthood exerts a minor impact. This suggests that early life is an important period in the determination of telome...

    Authors: Esmée M. Bijnens, Maurice P. Zeegers, Catherine Derom, Dries S. Martens, Marij Gielen, Geja J. Hageman, Michelle Plusquin, Evert Thiery, Robert Vlietinck and Tim S. Nawrot

    Citation: BMC Medicine 2017 15:205

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  13. Content type: Research article

    Direct-acting antivirals (DAAs) have revolutionized chronic hepatitis C (HCV) treatment, but real-world effectiveness among vulnerable populations, including uninsured patients, is lacking. This study was cond...

    Authors: Christina Yek, Carolina de la Flor, John Marshall, Cindy Zoellner, Grace Thompson, Lisa Quirk, Christian Mayorga, Barbara J. Turner, Amit G. Singal and Mamta K. Jain

    Citation: BMC Medicine 2017 15:204

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  14. Content type: Research article

    Accumulating evidence suggests that individual circulating saturated fatty acids (SFAs) are heterogeneous in their associations with cardio-metabolic diseases, but evidence about associations of SFAs with meta...

    Authors: Ju-Sheng Zheng, Stephen J. Sharp, Fumiaki Imamura, Albert Koulman, Matthias B. Schulze, Zheng Ye, Jules Griffin, Marcela Guevara, José María Huerta, Janine Kröger, Ivonne Sluijs, Antonio Agudo, Aurelio Barricarte, Heiner Boeing, Sandra Colorado-Yohar, Courtney Dow…

    Citation: BMC Medicine 2017 15:203

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  15. Content type: Research article

    The UK is dependent on international doctors, with a greater proportion of non-UK qualified doctors working in its universal health care system than in any other European country, except Ireland and Norway. Th...

    Authors: Aneez Esmail, Maria Panagioti and Evangelos Kontopantelis

    Citation: BMC Medicine 2017 15:191

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  16. Content type: Guideline

    Dietary assessment is complex, and strategies to select the most appropriate dietary assessment tool (DAT) in epidemiological research are needed. The DIETary Assessment Tool NETwork (DIET@NET) aimed to establ...

    Authors: Janet E. Cade, Marisol Warthon-Medina, Salwa Albar, Nisreen A. Alwan, Andrew Ness, Mark Roe, Petra A. Wark, Katharine Greathead, Victoria J. Burley, Paul Finglas, Laura Johnson, Polly Page, Katharine Roberts, Toni Steer, Jozef Hooson, Darren C. Greenwood…

    Citation: BMC Medicine 2017 15:202

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  17. Content type: Research article

    Childhood pneumonia is the leading infectious cause of mortality in children younger than 5 years old. Recent updates to World Health Organization pneumonia guidelines recommend outpatient care for a populatio...

    Authors: Timothy Tuti, Ambrose Agweyu, Paul Mwaniki, Niels Peek and Mike English

    Citation: BMC Medicine 2017 15:201

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    The Correction to this article has been published in BMC Medicine 2017 15:212

  18. Content type: Research article

    While the United States has the largest number of children with type 1 diabetes mellitus, less is known regarding adult-onset disease. The present study utilizes nationwide data to compare the incidence of typ...

    Authors: Mary A. M. Rogers, Catherine Kim, Tanima Banerjee and Joyce M. Lee

    Citation: BMC Medicine 2017 15:199

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  19. Content type: Research article

    Obesity is common in young women, increasing insulin resistance (IR) and worsening pregnancy complications, including gestational diabetes (GDM). Women with polycystic ovary syndrome (PCOS) are commonly obese,...

    Authors: Nadira Sultana Kakoly, Arul Earnest, Lisa J. Moran, Helena J. Teede and Anju E. Joham

    Citation: BMC Medicine 2017 15:195

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  20. Content type: Research article

    All obese pregnant women are considered at equal high risk with respect to complications in pregnancy and birth, and are commonly managed through resource-intensive care pathways. However, the identification o...

    Authors: Matias C. Vieira, Sara L. White, Nashita Patel, Paul T. Seed, Annette L. Briley, Jane Sandall, Paul Welsh, Naveed Sattar, Scott M. Nelson, Debbie A. Lawlor, Lucilla Poston and Dharmintra Pasupathy

    Citation: BMC Medicine 2017 15:194

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  21. Content type: Research article

    HIV-associated immune defects inhibit tuberculosis (TB) diagnosis, promote development of extrapulmonary TB and paucibacillary pulmonary TB cases with atypical radiographic features, and increase TB relapse ra...

    Authors: Jia Fan, Hedong Zhang, Duc T. Nguyen, Christopher J. Lyon, Charles D. Mitchell, Zhen Zhao, Edward A. Graviss and Ye Hu

    Citation: BMC Medicine 2017 15:188

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