A lesion followed over time. Coronal fluid attenuated inversion recovery (FLAIR) image. The arrow points to a small periventricular lesion. The lesion shows no difference during the time course. However, the thickness of the subcutaneous fat layer (see red circle) shows a marked decrease from (A-C) and recovery at (D). (A) Timepoint 1 before the TransEurope-FootRace 2009 (TEFR09) in April 2009; (B) timepoint 2 during the race at 2,326 km; (C) timepoint 3 during the race at 4,005 km; (D) timepoint 4 at follow-up 8 months after the race.