Figure 4
From: Insufficient maintenance DNA methylation is associated with abnormal embryonic development
The effect of DNMT1 inhibition on embryo implantation and DNA methylation level in vivo. A: The fetal number was significantly less in the uterine horn injected with DNMT1 inhibitor than in the control horn. The data are shown as means ± SEM. Procainamide group: n = 10; control group: n = 10. * P < 0.05. B: The global DNA methylation level was significantly lower in mouse embryos obtained from the uterine horn injected with DNMT1 inhibitor than in those from the control horn. The data are shown as means ± SEM. Procainamide group: n = 18; control group: n = 18. * P < 0.05. SEM, standard error of the mean.