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Figure 9 | BMC Medicine

Figure 9

From: Targeting the epidermal growth factor receptor in non-small cell lung cancer cells: the effect of combining RNA interference with tyrosine kinase inhibitors or cetuximab

Figure 9

Effect of combination of EGFR siRNA and afatinib with Hoechst 33342 and PI double fluorescent staining. Effect of the combination of an EGFR siRNA and afatinib detected by Hoechst 33342 and PI double fluorescent staining. The concentrations were afatinib: 0.01 nM (assayed 72 h post treatment) and EGFR siRNA: 200 nM (assayed 48 h post transfection). Similar results were found with other concentrations of afatinib, and other drugs in all the five cell lines (data not shown).

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