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Table 1 Relevant genotypic changes in the NSCLC cell lines studied

From: Targeting the epidermal growth factor receptor in non-small cell lung cancer cells: the effect of combining RNA interference with tyrosine kinase inhibitors or cetuximab

Cell lines EGFR status KRAS status PTEN
HCC827 Exon 19 deletion Wild-type +
H292 Wild-type Wild-type +
H358 Wild-type Mutant +
H1650 Exon 19 deletion Wild-type -
H1975 Exon 21 L858R + exon 20 T790M Wild-type +