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Table 1 Relevant genotypic changes in the NSCLC cell lines studied

From: Targeting the epidermal growth factor receptor in non-small cell lung cancer cells: the effect of combining RNA interference with tyrosine kinase inhibitors or cetuximab

Cell lines

EGFR status

KRAS status

PTEN

HCC827

Exon 19 deletion

Wild-type

+

H292

Wild-type

Wild-type

+

H358

Wild-type

Mutant

+

H1650

Exon 19 deletion

Wild-type

-

H1975

Exon 21 L858R + exon 20 T790M

Wild-type

+