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Table 1 Characteristics of the T1D subjects before treatment

From: Reversal of type 1 diabetes via islet β cell regeneration following immune modulation by cord blood-derived multipotent stem cells

Patient
No.
Age Gender Marriage History
(year)
Height
(cm)
Body
weight
(kg)
C-peptide
(ng/ml)*
Auto-Antibodies HbA1C
(%)
Insulin dose
(U/day)
         IA-2A GAD ICA IAA   
Group A: Long-standing patients having some residual islet β cell function and received therapy with CB-SC
1 17 F No 5 145 35 0.30 - + - - 12.3 52
2 23 F No 5 167 59 0.56 - + - - 6.6 50
3 38 F Yes 11 160 60 0.12 - + - - 7.3 23
4 39 F Yes 1 156 49 0.636 + + + - 11.3 22
5 31 M Yes 14 170 70 0.18 + + - - 6.5 30
6 30 M Yes 2 182 70 0.18 - + - - 8.4 40
Mean
(SD)
30
(9)
   6
(5)
163
(12.7)
57
(13.4)
0.33
(0.22)
     8.7
(2.5)
36.2
(13.2)
Group B: Long-standing severe patients with no residual islet b cell function and received therapy with CB-SC
7 40 M Yes 17 170 72.5 0.01 - + - - 8.8 48
8 15 F No 5 163 65 0.01 - + - - 15.5 50
9 21 F No 4 168 65 0.01 + - - - 9.9 46
10 23 F No 12 162 80 0.01 + + + - 16.5 60
11 40 F Yes 21 160 67 0.01 + - - - 8.6 37
12 21 F No 5 157 56 0.01 - + - - 13.6 50
Mean
(SD)
27
(11)
   11
(7)
163
(4.9)
67.6
(8.1)
0.01
(0)
     12.2
(3.5)
48.5
(7.4)
Control group: Long-standing patients having some residual islet β cell function and received sham therapy
13 35 M Yes 1 178 73.5 0.37 + - + - 9.8 30
14 41 M Yes 14 165 65 0.55 - + - - 6.4 48
15 24 M No 3 175 58 0.3 - + - - 10.7 48
Mean
(SD)
33
(9)
   6
(7)
173
(6.8)
65.5
(7.8)
0.41
(0.13)
     9.0
(2.3)
42
(10.4)
  1. *The level of 0.01 ng/ml is the minimum detectable level (sensitivity) of C-peptide by radioimmunoassay (RIA). To convert C-peptide value to nmol/L, multiply the ng/ml by 0.331.