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Figure 9 | BMC Medicine

Figure 9

From: Mitochondrial aldehyde dehydrogenase (ALDH2) protects against streptozotocin-induced diabetic cardiomyopathy: role of GSK3β and mitochondrial function

Figure 9

Phosphorylation of Akt, GSK3β, mTOR and Foxo3a in myocardium from FVB and ALDH2 mice treated with or without streptozotocin. (A) pAkt-to-Akt ratio; (B) pGSK3β-to-GSK3β ratio; (C) pmTOR-to-mTOR ratio; (D) pFoxo3a-to-Foxo3a ratio. Insets: representative gel blots of pan and phosphorylated Akt, GSK3β, mTOR and Foxo3a (GAPDH as loading control) using specific antibodies. Mean ± SEM, n = 6 to 7 mice per group. *P < 0.05 versus FVB group; # P < 0.05 versus FVB-STZ group.

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