Phosphorylation of Akt, GSK3β, mTOR and Foxo3a in myocardium from FVB and ALDH2 mice treated with or without streptozotocin. (A) pAkt-to-Akt ratio; (B) pGSK3β-to-GSK3β ratio; (C) pmTOR-to-mTOR ratio; (D) pFoxo3a-to-Foxo3a ratio. Insets: representative gel blots of pan and phosphorylated Akt, GSK3β, mTOR and Foxo3a (GAPDH as loading control) using specific antibodies. Mean ± SEM, n = 6 to 7 mice per group. *P < 0.05 versus FVB group; #
P < 0.05 versus FVB-STZ group.