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Table 1 Correlation between FSSG scores and 25 background factors of the 19,864 participants (univariate analyses).

From: Lifestyle factors affecting gastroesophageal reflux disease symptoms: a cross-sectional study of healthy 19864 adults using FSSG scores

Factors FSSG scores of the applicable subjects to the factor FSSG scores of the inapplicable subjects to the factor P-value
Gender (female) 5.1 ± 5.4 (8,371) 4.6 ± 5.1 (11,493) < 0.0001 *
History of gastrectomy 5.9 ± 6.0 (210) 4.8 ± 5.2 (19,654) 0.0019 *
Use of PPIs 9.0 ± 7.3 (371) 4.7 ± 5.1 (19,493) < 0.0001 *
Use of H2RAs 8.2 ± 6.6 (539) 4.7 ± 5.1 (19,325) < 0.0001 *
Use of other digestive drugs 8.2 ± 6.5 (985) 4.6 ± 5.1 (18,879) < 0.0001 *
Use of NSAIDs 6.9 ± 5.8 (1,076) 4.7 ± 5.2 (18,788) < 0.0001 *
Use of steroids 6.1 ± 6.1 (214) 4.8 ± 5.2 (19,650) 0.0002 *
Use of anticoagulants 4.7 ± 4.9 (572) 4.8 ± 5.2 (19,292) 0.6056
Use of antihypertensive drugs 4.6 ± 5.1 (2,581) 4.8 ± 5.2 (17,283) 0.0967
Use of antihyperglycemic agents 3.8 ± 4.3 (561) 4.8 ± 5.2 (19,303) < 0.0001 *
Use of antihyperlipidemic agents 4.7 ± 5.2 (1,728) 4.8 ± 5.2 (18,136) 0.3572
History of cerebrovascular disease 4.8 ± 5.1 (289) 4.8 ± 5.2 (19,575) 0.9675
History of cardiovascular disease 5.6 ± 5.7 (554) 4.8 ± 5.2 (19,310) 0.0002 *
History of renal failure 4.8 ± 5.2 (86) 4.8 ± 5.2 (19,778) 0.8984
Increased body weight in adulthood 5.2 ± 5.5 (7,449) 4.5 ± 5.0 (12,415) < 0.0001 *
Lack of habitual physical exercise 5.0 ± 5.3 (14,988) 4.1 ± 4.8 (4,876) < 0.0001 *
Habit of midnight snack 5.9 ± 6.0 (3,180) 4.6 ± 5.0 (16,684) < 0.0001 *
Inadequate sleep 6.0 ± 5.8 (7,988) 4.0 ± 4.6 (11,876) < 0.0001 *
Frequent lack of breakfast 5.9 ± 6.0 (2,709) 4.6 ± 5.1 (17,155) < 0.0001 *
Dinner just before bedtime 5.6 ± 5.8 (6,035) 4.4 ± 4.9 (13,829) < 0.0001 *
Habit of quick eating 5.0 ± 5.3 (7,652) 4.6 ± 5.1 (12,212) < 0.0001 *
Habit of smoking 5.0 ± 5.3 (3,981) 4.7 ± 5.2 (15,883) 0.0013 *
Habit of alcohol drinking 4.8 ± 5.2 (6,553) 4.8 ± 5.2 (13,311) 0.9618
Age r = -0.06 < 0.0001 *
BMI r = -0.01 0.2399
  1. BMI, body mass index; H2RAs, histamine H2-receptor antagonists; NSAIDs, non-steroidal anti-inflammatory drugs; PPIs, proton pump inhibitors; r, regression coefficient. Except for age and BMI, the Student's t-test was used to evaluate the correlation between each background factor and the FSSG score (mean ± standard deviation is shown). The correlation of FSSG score with age or BMI was assessed using Pearson's correlation coefficient. The levels of significance in these univariate analyses were set at P-value < 0.05 (*).