Author/Year [ref] | Study design | No of patients | Site | Size of defect | Etiology | Type of membrane | Graft | Type of fixation | Evaluation | Outcome |
---|---|---|---|---|---|---|---|---|---|---|
Meining 2010 [13] | case series | Six | Tibia (five) Femur (one) | ≥ CSD | Trauma | poly(L/DL-lactide) 80/20% membranes with 50 to 70 μm pore size | RIA, ICBG | IMN, plating | X-rays | Healing one case: re-grafting after 15 months |
Ip 2004 [134] | case series | Ten | Not reported | ≤ 6 cm | Benign tumor, Osteomyelitis and trauma |  | polymeric scaffolds (sponges, 450 to 700 μm pore size) impregnated with bone marrow | Not reported | X-rays | Presence of bone regeneration and satisfactory function |