Table 4 Median biomarker levels in patient clusters.
Biomarker (units) | Median (inter quartile range) in patient clusters | ||||
|---|---|---|---|---|---|
| Â | blue | red | green | purple | gold |
BLACK CLUSTER | |||||
CRP (ng/ml) | 1.05 (0.74 to 1.33) | 0.86 (<0.67 to 0.91) | 1.06 (0.84 to 1.25) | <0.67 (<0.67 to 0.83) | 0.75 (<0.67 to 0.90) |
TNFα (pg/ml) | 10.52 (7.78 to 13.25) | 9.07 (7.36 to 9.79) | 9.54 (7.46 to 11.78) | 11.66 (8.95 to 15.48) | 10.20 (8.31 to 12.820) |
GREEN CLUSTER | |||||
EGF (pg/ml) | 7,056 (4,965 to 13,752) | 3,633 (1,874 to 5,992) | 6,477 (2,784 to 10,943) | 3,722.33 (3,058 to 4,956) | 13,826 ( 9,488 to 20,332) |
sTNFR1(pg/ml) | 0.67 (0.41 to 1.04) | 0.75 (0.47 to 1.05) | 0.57 (0.24 to 1.61) | 0.74 (0.45 to 1.06) | 1.60 (0.97 to 2.54) |
PURPLE CLUSTER | |||||
CK18 (ng/ml) | 2.30 (0.71 to 3.59) | 1.22 (0.42 to 2.78) | 2.03 (0.75 to 4.33) | 8.97 (2.88 to 21.43) | 6.43 (2.67 to 10.28) |
MCP-1 (pg/ml) | 112 (38 to 212) | 73 (41 to 141) | 67 (28 to 113) | 269 (118 to 871) | 237 (106 to 550) |
NSE (ng/ml) | IQR below LOD | 0.28 (<0.26 to 0.92) | IQR below LOD | 1.72 (<0.26 to 18.32) | 0.51 (< 0.26 to 2.37) |
MMP-9 (ng/ml) | IQR below LOD | IQR below LOD | IQR below LOD | 15.15 (6.57 to 50.81) | IQR below LOD |
IL-6 (pg/ml) | 1.37 (<1.20 to 3.60) | 12.93 (3.27 to 26.67) | <1.20(<1.20 to 2.50) | 194.33 (16.43 to 577.33) | 40.80 (4.80 to 196.67) |
vWF (IU/ml) purple | 0.01 (0.01 to 0.02) | 0.01 (0.00 to 0.01) | 0.01 (0.01 to 0.01) | 0.01 (0.01 to 0.02) | 0.01 (0.01 to 0.03) |
GOLD CLUSTER | |||||
Protein (mg/ml) | 0.07 (0.05 to 0.11) | 0.44(0.29 to 0.60) | 0.08 (0.05 to 0.12) | 0.59 (0.25 to 0.93) | 0.30 (0.09 to 1.00) |
NGAL (ng/ml) | 123 (92 to 212) | 192 (146 to 297) | 110 (74 to 148) | 1,379 (602 to 1922) | 464 (108 to 1368) |
D-dimer (ng/ml) | <2.10 (<2.10 to 5.02) | 47.01 (11.80 to 138.27) | <2.10 (<2.10 to 3.62) | 597.89 (62.16 to 1493.69) | 58.35 (<2.10 to 559.38) |
IL-1α (pg/ml) | 0.90 (0.90 to 2.52) | 2.42 (1.01 to 3.53) | 0.90 (0.90 to 1.01) | 21.35 (5.80 to 30.93) | 2.47 (0.90 to 81.00) |
IL-1β (pg/ml) | IQR below LOD | IQR below LOD | IQR below LOD | 17.80 (5.46 to 78.87) | <1.60 (<1.60 to 19.12) |
PINK CLUSTER | |||||
IL-8 (pg/ml) | 32.40 (7.93 to 265.83) | 292.67 (117.33 to 604.33) | 28.63 (7.90 to 135.33) | 2,900 (2,064 to 2,900) | 875.67 (48.40 to 2,900) |
MMP9NGAL | 0.09 (0.08 to 0.10) | 0.16 (0.10 to 0.29) | 0.07 (0.07 to 0.09) | 0.29 (0.23 to 0.48) | 0.23 (0.09 to 0.29) |
IL-4 (pg/ml) | IQR below LOD | IQR below LOD | IQR below LOD | <6.60 (<6.60 to 6.80) | IQR below LOD |
sTNFR2 (pg/ml) | IQR below LOD | <0.15 (<0.15 to 0.26) | <0.15 (<0.15 to 0.26) | IQR below LOD | <0.15 (<0.15 to 0.61) |
BLUE CLUSTER | |||||
creatinine (µmol/L) | 9,608 (7,961 to 13,360) | 5,605 (4,454 to 11,945) | 7,115 (3,868 (12,595) | 7,600 (5,360 to 8,625) | 14,087 (12,405 to 17,245) |
osmolarity (mOsm) | 536 (450 to 741) | 462 (276 to 560) | 526 (278 to 675) | 404 (314 to 482) | 644 (567 to 7,840) |
TM (ng/ml)blue | 4.08 (3.19 to 4.97) | 3.97 (1.55 to 5.69) | 4.00 (1.74 to 5.68) | 3.49 (2.65 to 4.00) | 6.30 (5.34 to 8.86) |
YELLOW CLUSTER | |||||
IL-2 (pg/ml) | 5.61 (5.21 to 5.92) | 5.24 (5.02 to 5.65) | 5.45 (5.20 to 6.27) | 6.89 (5.99 to 7.24) | 5.99 (5.65 to 7.20) |
CEA (ng/ml) | 1.57 (1.16 to 2.58) | 1.59 (1.15 to 3.23) | 1.36 (0.87 to 2.10) | 1.77 (1.30 to 2.39) | 1.37 (0.89 to 2.80) |
HA (ng/ml) | 685 (439 to 866) | 835 (595 to 1005) | 594 (282 to 900) | 1,569 (1,143 to 1,846) | 1,258 (883 to 1,712) |
FPSA (ng/ml) | 0.09 (0.04 to 0.21) | 0.05 (0.04 to 0.23) | 0.07 (0.04 to 0.12) | 0.13 (0.07 to 0.30) | 0.05 (0.04 to 0.10) |
BTA (U/ml) | 8.52 (2.57 to 38.96) | 248.01 (206.82 to 394.15) | 6.27 (1.21 to 17.92) | 278.41 (226.40 to 504.33) | 213.00 (15.24 to 476 .28) |
VEGF (ng/ml) | 88 (37 to 271) | 96 (76 to 220) | 78 (38 to 122) | 1,266 (414 to 1,500) | 253 (79 to 621) |
FAS (pg/ml) | 64 (42 to 96) | 83 (60 to 128) | 56 (37 to 86) | 214 (106 to 475) | 200 (96 to 279) |