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Table 3 Characteristics of hospitalized adults who tested positive (cases) and negative (controls) for Clostridium difficile

From: Depression, antidepressant medications, and risk of Clostridium difficileinfection

Characteristics Cases, n = 468 Controls, n = 3579 Pvalue
Age, mean ± SDa 57.6 ± 17.5 58.8 ± 16.5 0.158
Female, n (%) 223 (47.6) 1723 (48.1) 0.841
Caucasian, n (%) 387 (82.7) 2927 (81.8)  
African-American, n (%) 51 (10.9) 386 (10.8)  
Other race/unknown, n (%) 30 (6.4) 266 (7.4) 0.727
Elective admission, n (%) 138 (29.5) 930 (26.0)  
Urgent admission, n (%) 104 (22.2) 846 (23.6)  
Emergent admission, n (%) 226 (48.3) 1803 (50.4) 0.268
Days until stool collection, median (IQR)b 6 (4 to 10) 6 (4 to 10) 0.273
Antibiotics, n (%) 392 (83.8) 2956 (82.6) 0.530
Immunosuppressants, n (%) 71 (36.4) 554 (35.0) 0.692
Proton-pump inhibitors, n (%) 268 (57.3) 2040 (57.0) 0.913
Histamine-2 receptor antagonists, n (%) 138 (29.5) 1061 (29.6) 0.944
Statins, n (%) 130 (27.8) 927 (25.9) 0.385
Anxiolytics, n (%) 67 (34.4) 499 (31.5) 0.419
Antipsychotics, n (%) 24 (12.3) 202 (12.7) 0.860
  1. aAge range 18 to 100 years.
  2. bNumber of days from admission to stool collection for Clostridium difficile testing, median and interquartile range (IQR).