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Figure 1 | BMC Medicine

Figure 1

From: Peripheral blood monocyte-to-lymphocyte ratio at study enrollment predicts efficacy of the RTS,S malaria vaccine: analysis of pooled phase II clinical trial data

Figure 1

RTS,S vaccine efficacy estimates at different levels of ML ratio measured before vaccination. In (A), the predicted efficacy (bold line) and 95% confidence intervals (dashed lines) of the RTS,S vaccine are shown in relation to the pre-vaccination ML ratio following bootstrap analysis of a Cox regression model predicting time to first clinical malaria episode with RTS,S vaccination, pre-vaccination ML ratio and an interaction term for both variables as covariates. In (B), the distribution of pre-vaccination ML ratios for all the 610 children included in the study is shown.

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