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Table 5 Neonatal and maternal mortality outcomes by treatment for all clusters

From: A combined community- and facility-based approach to improve pregnancy outcomes in low-resource settings: a Global Network cluster randomized trial

 

Group

 
 

Intervention

Control

P-value

Clusters, N

53

53

 

Outcomes for full intervention period

   

Births ≥1000 g, N

56,223

55,306

 

Outcomes - Mean (95% CI)

   

  Perinatal mortality (<7 days) (Rate/1,000)

40.1 (37.3, 42.9)

40.1 (37.4, 42.8)

0.9996

  Stillbirths (Rate/1,000)

21.8 (19.8, 23.9)

22.6 (20.5, 24.6)

0.6177

  Fresh stillbirth (Rate/1,000)

15.2 (13.4, 17.0)

15.5 (14.0, 17.0)

0.8082

  Early neonatal mortality (<7 days) (Rate/1,000)

18.7 (17.3, 20.1)

18.2 (16.6, 19.7)

0.5950

  Neonatal mortality (<28 days) (Rate/1,000)

23.8 (22.0, 25.5)

22.5 (20.6, 24.5)

0.3362

  Fresh stillbirths + neonatal deaths <7 days (Rate/1,000)

33.8 (31.2, 36.3)

33.4 (31.2, 35.5)

0.8105

  Maternal mortality (<42 days) (Rate/100,000)

125.1 (97.7, 160.2)

130.9 (104.5, 163.9)

0.7321

Outcomes for final six months of intervention period

   

Births ≥1,000 g, N

15,412

15,180

 

Outcomes - Mean (95% CI)

   

  Perinatal mortality (<7 days) (Rate/1,000)

39.6 (35.8, 43.4)

41.4 (37.4, 45.5)

0.5043

  Stillbirths (Rate/1,000)

21.6 (18.8, 24.4)

22.9 (19.7, 26.2)

0.5491

  Fresh stillbirth (Rate/1,000)

15.2 (12.7, 17.7)

14.5 (12.2, 16.8)

0.6826

  Early neonatal mortality (<7 days) (Rate/1,000)

18.7 (16.7, 20.8)

19.0 (16.8, 21.3)

0.8458

  Neonatal mortality (<28 days) (Rate/1,000)

23.4 (21.0, 25.8)

22.9 (20.3, 25.6)

0.7822

  Fresh stillbirths + neonatal deaths <7 days (Rate/1,000)

33.4 (30.1, 36.8)

33.4 (30.3, 36.4)

0.9734

  Maternal mortality (<42 days) (Rate/100,000)

109.1 (64.5, 184.5)

78.3 (44.0, 139.3)

0.2799

Outcomes for 12-months post-intervention period

   

Births ≥1,000 g, N

27,852

26,356

 

Outcomes - Mean (95% CI)

   

  Perinatal mortality (<7 days) (Rate/1,000)

37.9 (34.0, 41.7)

36.6 (33.2, 40.0)

0.6202

  Stillbirths (Rate/1,000)

21.7 (19.2, 24.2)

21.1 (18.9, 23.4)

0.7406

  Fresh stillbirth (Rate/1,000)

14.8 (12.7, 16.9)

14.1 (12.2, 16.0)

0.6271

  Early neonatal mortality (<7 days) (Rate/1,000)

16.4 (14.5, 18.4)

15.9 (13.8, 18.0)

0.7136

  Neonatal mortality (<28 days) (Rate/1,000)

21.4 (19.0, 23.8)

20.0 (17.5, 22.5)

0.4311

  Fresh stillbirths + neonatal deaths <7 days (Rate/1,000)

31.3 (27.7, 34.9)

29.7 (26.6, 32.9)

0.5126

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