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Table 5 ADR risk factors assessed by multivariate analysis

From: Adverse drug reactions and off-label and unlicensed medicines in children: a nested case?control study of inpatients in a pediatric hospital

Covariate

HR (95% CI)

P-value

Gender

Female

1

0.152

Male

0.896 (0.770 to 1.042)

Age on admission (years)

 

1.036 (1.021 to 1.052)

<0.001

Received a GA

No

1

<0.001

Yes

5.295 (4.417 to 6.349)

Oncology

No

1

0.655

Yes

0.926 (0.661 to 1.298)

Number of authorized medicines

1.217 (1.171 to 1.263)

<0.001

Number of off-label and/or unlicensed medicines

1.267 ( 1.201 to 1.336)

<0.001

Number of uncategorized medicines

1.138 (0.969 to 1.338)

0.116

  1. ADR, adverse drug reaction; CI, confidence interval; GA, general anesthesia; HR, hazard ratio.