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Table 2 Linear Regression Models: methylation at the IGF2 and H19 DMRs in relation to parental obesity

From: Paternal obesity is associated with IGF2hypomethylation in newborns: results from a Newborn Epigenetics Study (NEST) cohort

Linear regression models IGF2DMR H19DMR
  Obesity of: β SE P β SE P
Model 1 Father -3.83 1.48 0.01 +3.09 1.64 0.07
Model 2 Mother +2.38 1.30 0.08 +2.80 1.38 0.05
Model 3 Father
Mother
-5.28
+3.08
1.62
1.48
0.003
0.05
+2.55
+1.05
1.82
1.70
0.17
0.54
  1. Obesity was defined as BMI ≥30 kg/m2. All models were adjusted for maternal age and smoking status, as well as by the newborn's birth weight and gender. Models 1 and 2 include either maternal or paternal obesity. Model 3 includes both maternal and paternal obesity.